Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC156461 GAPDH 7 Median: 35000000
Range: 35000 to 100000000
IC50 PMID: 7562915
PMID: 7562915
PMID: 7562915
PMID: 7932587
PMID: 7932587
PMID: 7932587
PMID: 9822549
NPC156461 ADORA2B 3 Median: 24000
Range: 24000 to 24000
EC50 PMID: 20541935
PMID: 21388809
PMID: 24164628
NPC156461 SLC29A1 1 17000 IC50 PMID: 23388705
NPC180905 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC180905 HPGD 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC48342 CACNA1C 1 50000 IC50 PMID: 22761000
NPC48342 NR3C1 1 41422 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC48342 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC48342 GPBAR1 1 38400 EC50 PMID: 18307294
NPC48342 ALDH1A1 1 37650.5 Potency PubChem BioAssay data set
CHEMBL1201862
NPC48342 RECQL 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC48342 HSD17B10 2 Median: 22535.75
Range: 19952.6 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC48342 SLC6A3 1 14911 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC98028 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC98028 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC98028 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156461 MAPK1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC190501 HTR2B 1 13630 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC48342 SLC6A4 1 10755 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046