Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC161749 SMN1;SMN2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC39426 SYK 1 39000 IC50 PMID: 19254842
NPC39426 ALDH1A1 2 Median: 37646
Range: 35481.3 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC39426 NR1H3 1 31000 IC50 PMID: 18343126
NPC39426 DNMT1 1 30000 IC50 PMID: 25406944
NPC39426 ODC1 1 26000 IC50 PMID: 10075742
NPC39426 PKM 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC39426 SMN1;SMN2 3 Median: 25118.9
Range: 22387.2 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC39426 NR1H2 1 22000 IC50 PMID: 18343126
NPC39426 AKR1B1 1 20000 IC50 PMID: 22261024
NPC39426 ALOX15 2 Median: 25787.7
Range: 19952.6 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC39426 ADORA1 1 19904 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC39426 ADORA2A 1 17442 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC39426 PMP22 1 16944.1 Potency PubChem BioAssay data set
CHEMBL1201862
NPC39426 SLC6A3 1 16918 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC39426 HSD17B2 1 16500 IC50 PMID: 18533708
NPC39426 LMNA 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC39426 HTR2C 1 14910 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC87545 POLB 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87545 GAA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234333 PTGS1 1 12000 IC50 PMID: 16038536
NPC39426 HPGD 4 Median: 19952.6
Range: 11220.2 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC39426 HTR2A 1 10469 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC87545 MAPT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862