Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC110396 MAPK1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110396 SMN1;SMN2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 KDM4E 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 TP53 2 Median: 23735.85
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC115159 TP53 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC115159 ALOX15 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC115159 CYP2C9 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC115159 PKM 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC115159 CYP2D6 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC120066 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 BACE1 1 33000 IC50 DOI: 10.1007/s00044-012-0353-y
NPC19174 NPSR1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 KMT2A 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 MTOR 1 26121.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 APP 1 19700 IC50 PMID: 23786711
NPC19174 GMNN 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 PMP22 1 15101.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214036 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214036 MAPK1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214036 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231772 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231772 TDP1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231772 TP53 2 Median: 28370.85
Range: 25118.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC259767 DPP4 1 26920 IC50 DOI: 10.1039/C0MD00245C
NPC74881 CD38 1 37900 IC50 PMID: 21641214
NPC115159 CYP2C19 1 12589.25 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC120066 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 CHRNA7 1 11600 EC50 PMID: 25232969
NPC231772 LMNA 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231772 SMN1;SMN2 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC231772 USP2 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC231772 CYP2D6 1 12589.25 AC50 PubChem BioAssay data set
CHEMBL1201862