Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC100551 CA14 1 49800 Ki PMID: 18579385
NPC100551 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100551 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100551 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100551 HPGD 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC10251 L3MBTL1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103213 UGT1A1 2 Median: 43500
Range: 40000 to 47000
IC50 PMID: 21030469
PMID: 21030469
NPC103213 ALOX15 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103213 MAPT 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC1075 CYP2C9 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110899 CA5B 1 35400 Ki PMID: 20185318
NPC113733 POLB 2 Median: 51840
Range: 43400 to 60280
IC50 PMID: 14640519
PMID: 18343122
NPC116775 BCHE 1 43100 Ki PMID: 19879672
NPC116775 ALDH1A1 2 Median: 35716.75
Range: 31622.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC116775 CDK6 2 Median: 22000
Range: 22000 to 22000
IC50 PMID: 15689157
DOI: 10.1007/s00044-009-9233-5
NPC116775 GLO1 1 20600 IC50 PMID: 18258440
NPC116775 KDM4E 2 Median: 27829.8
Range: 15848.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 HSD17B10 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 BACE1 1 14700 IC50 DOI: 10.1007/s00044-012-0353-y
NPC124512 NFKB1 1 49600 IC50 PMID: 25615020
NPC129976 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC131623 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC133671 P4HB 1 19020 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC142319 TYR 2 Median: 130130
Range: 30260 to 230000
IC50 PMID: 16872137
PMID: 17693086
NPC145038 MPI 1 21303 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC149155 HTT 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC149184 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC149184 PPARD 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC149184 PPARA 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC149209 HDAC1 1 16000 IC50 PMID: 21874153
NPC149209 HDAC8 1 15000 IC50 PMID: 21874153
NPC155763 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 L3MBTL1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 POLB 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC160193 SLC6A4 1 46700 Ki PMID: 24187998
NPC160193 MAOB 1 29000 Ki PMID: 24187998
NPC160193 MAOA 1 27000 Ki PMID: 24187998
NPC169433 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC169749 DPP4 1 37150 IC50 DOI: 10.1039/C0MD00245C
NPC169749 ALPL 1 33200 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC169749 ALPPL2 1 32300 EC50 PubChem BioAssay data set
CHEMBL1201862
NPC169749 KMT2A 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC169749 AMY1A;AMY1B;AMY1C 1 30200 IC50 PMID: 18507367
NPC169749 AKR1B1 1 29000 IC50 PMID: 18165015
NPC169749 CD38 1 24800 IC50 PMID: 21641214
NPC169749 DAPK1 1 23000 IC50 PMID: 26322379
NPC169749 ABCC2 1 22000 IC50 PMID: 19725578
NPC169749 ABCC1 1 20000 IC50 PMID: 19725578
NPC169749 CYP2D6 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC169749 APOBEC3A 1 17500 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC169749 MTOR 2 Median: 19881.25
Range: 16481.6 to 23280.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC169749 BLM 3 Median: 14125.4
Range: 14125.4 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC169749 ALOX12 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC171736 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC171736 PPARA 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC171736 PPARD 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC176740 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC176740 EPHX2 1 24300 IC50 PMID: 24679441
NPC176740 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC179092 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC179092 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC179092 F3 1 32000 IC50 PMID: 9834151
NPC179092 MAPT 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC179950 EPHX2 1 28430 IC50 PMID: 24679441
NPC179950 XDH 1 26310 IC50 PMID: 12444671
NPC179950 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC181465 XDH 1 14800 IC50 PMID: 9461655
NPC185838 ALDH1A1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC185838 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC185838 HSD17B10 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC185838 ALOX15 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC189470 PTPRCAP 1 17000 IC50 DOI: 10.1016/0960-894X(95)00250-W
NPC194856 MAOA 1 25000 IC50 PMID: 15482934
NPC194856 FASN 1 17850 IC50 PMID: 20817450
NPC203468 TSHR 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203468 MAPT 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203468 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203468 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 CA14 2 Median: 48900
Range: 48900 to 48900
Ki PMID: 18579385
PMID: 20185318
NPC204932 BLM 2 Median: 44668.4
Range: 44668.4 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 POLB 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 APEX1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 EGFR 1 26043 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC204932 MMP9 1 23367 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC204932 TDP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 L3MBTL1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 FYN 1 17431 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC204932 RECQL 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 ALOX15 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC20791 PMP22 1 47754.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC20791 THRB 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC20791 GALK1 1 42128.5 Potency PubChem BioAssay data set
CHEMBL1201862
NPC20791 CDK2 1 40000 IC50 PMID: 17178224
NPC20791 CD38 1 37900 IC50 PMID: 21641214
NPC20791 SORD 2 Median: 106300
Range: 35600 to 177000
IC50 PMID: 8893834
PMID: 12672241
NPC20791 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC20791 EPHX2 1 33540 IC50 PMID: 24679441
NPC20791 DPP4 2 Median: 81365
Range: 32730 to 130000
IC50 PMID: 18650094
DOI: 10.1039/C0MD00245C
NPC20791 MAPK1 2 Median: 35716.75
Range: 31622.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC20791 ADORA3 1 30000 Ki PMID: 8576921
NPC20791 PTGS2 1 28600 IC50 PMID: 17378609
NPC20791 BLM 3 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC20791 TDP1 2 Median: 26651.35
Range: 25118.9 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC20791 ALDH1A1 6 Median: 37646
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC20791 CDK6 2 Median: 25000
Range: 25000 to 25000
IC50 PMID: 15689157
DOI: 10.1007/s00044-009-9233-5
NPC20791 PTPN1 2 Median: 23300
Range: 23300 to 23300
IC50 PMID: 12419367
PMID: 19297174
NPC20791 KMT2A 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC20791 AMY1A;AMY1B;AMY1C 1 21400 IC50 PMID: 18507367
NPC20791 SYK 1 20000 IC50 PMID: 22257213
NPC20791 HPGD 2 Median: 21169.9
Range: 19952.6 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC20791 APEX1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC20791 CYP2D6 1 18800 IC50 PMID: 22328583
NPC20791 USP2 2 Median: 25057.75
Range: 18492.7 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC20791 GPR35 1 15400 IC50 PMID: 24900447
NPC20791 APP 1 15300 IC50 PMID: 26719209
NPC209970 ALOX15 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC209970 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC209970 TDP1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC209970 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214067 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC214067 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC216630 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC219876 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 PTGS1 2 Median: 58350
Range: 36700 to 80000
IC50 PMID: 11858749
PMID: 16038536
NPC219876 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 NPSR1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 BLM 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 RECQL 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 MAPT 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 APEX1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 SELL 1 27600 IC50 PMID: 17302397
NPC225710 GAPDH 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 MAPK1 2 Median: 23753.05
Range: 22387.2 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC225710 SELP 1 19100 IC50 PMID: 17302397
NPC225710 SMN1;SMN2 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC226066 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC226066 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC226066 ALDH1A1 3 Median: 18869.9
Range: 14125.4 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC23155 MAPT 2 Median: 28370.85
Range: 25118.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC255042 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC258046 MAOB 1 15000 Ki PMID: 19786608
NPC261619 BACE1 2 Median: 25500
Range: 23000 to 28000
IC50 PMID: 14592472
PMID: 14592472
NPC261831 BLM 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 CYP19A1 1 32700 IC50 PMID: 16643058
NPC261831 TOP1 1 31000 IC50 PMID: 12444712
NPC261831 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 FABP4 1 26100 IC50 PMID: 20471252
NPC261831 KMT2A 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 ATM 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 HSD17B10 2 Median: 17900.75
Range: 15848.9 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC264317 POLB 2 Median: 44925
Range: 43600 to 46250
IC50 PMID: 14640519
PMID: 18343122
NPC264317 GLI1 2 Median: 32000
Range: 32000 to 32000
IC50 PMID: 18842418
PMID: 19309080
NPC268503 KCNH2 1 16000 IC50 PMID: 15324906
NPC26960 PTPN1 1 32600 IC50 PMID: 25497963
NPC279121 GALK1 1 47269 Potency PubChem BioAssay data set
CHEMBL1201862
NPC279121 THRB 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC279121 TSHR 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC279121 CYP2C9 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC279121 CYP2D6 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC279121 GAA 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC279121 DAPK1 1 21000 IC50 PMID: 26322379
NPC279121 CDK2 1 20000 IC50 PMID: 17178224
NPC279121 TDP1 2 Median: 29881.65
Range: 19952.6 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC279121 ABCB1 1 19600 IC50 PMID: 15240100
NPC279121 GPR35 1 18600 IC50 PMID: 24900447
NPC279121 AMY1A;AMY1B;AMY1C 1 18400 IC50 PMID: 18507367
NPC279121 MMP3 1 16200 IC50 PMID: 22658537
NPC279121 CYP2C19 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC279121 BLM 2 Median: 17900.75
Range: 15848.9 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC281131 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 MAPT 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 LMNA 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 EPHX2 1 21760 IC50 PMID: 24679441
NPC289774 TDP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC291066 ALOX12 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC291066 CYP2A6 2 Median: 25001.725
Range: 25000 to 25003.45
IC50 PMID: 15658857
PMID: 19110342
NPC294548 CYP19A1 1 44200 IC50 PMID: 16643058
NPC294548 BLM 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294548 L3MBTL1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294548 F3 1 30000 IC50 PMID: 9834151
NPC294548 HPGD 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294548 MAPT 3 Median: 28183.8
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294548 LMNA 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294548 PLA2G1B 1 22300 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC294548 KDM4E 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294548 PPARD 1 16000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC294548 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294548 ATG4B 1 15300 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC294902 HPGD 3 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294902 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294902 APEX1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294902 APP 1 32800 IC50 PMID: 22921742
NPC294902 AKR1B1 1 32000 IC50 PMID: 22236472
NPC294902 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294902 POLB 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC300326 PTGS1 1 39200 IC50 PMID: 22386242
NPC300326 PTGS2 1 28000 IC50 PMID: 22386242
NPC301585 PPARD 1 24000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC301585 PPARG 1 21000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC306902 GAA 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC306902 POLB 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC36835 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC36835 RECQL 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC36835 MMP13 1 34600 IC50 PMID: 22658537
NPC36835 ADORA3 1 34100 Ki PMID: 8576921
NPC36835 MMP3 1 33910 IC50 PMID: 22658537
NPC36835 MMP9 1 32020 IC50 PMID: 22658537
NPC36835 GMNN 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC36835 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC36835 MMP2 1 22620 IC50 PMID: 22658537
NPC36835 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC38779 ACHE 1 28000 IC50 PMID: 20053484
NPC53545 L3MBTL1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC60538 BCHE 1 46770 IC50 PMID: 24726809
NPC61477 HPGD 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC61477 MAPK1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC61477 RECQL 2 Median: 77689.6
Range: 14125.4 to 141253.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC70744 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC81010 ESR1 1 16120 EC50 PMID: 23608764
NPC85813 CYP19A1 1 48000 IC50 PMID: 16643058
NPC85813 F3 1 41000 IC50 PMID: 9834151
NPC85813 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85813 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 ALDH1A1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC9743 HIF1A 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC9743 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC100551 CA6 2 Median: 1165950
Range: 11900 to 2320000
Ki PMID: 18579385
PMID: 21669522
NPC100551 CA4 1 11100 Ki PMID: 18579385
NPC10251 TSHR 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC103213 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC1075 KDM4E 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110899 CA4 1 10600 Ki PMID: 20185318
NPC116775 MAPT 2 Median: 14219.1
Range: 12589.3 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC145038 GAA 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC149209 HDAC2 1 12000 IC50 PMID: 21874153
NPC155763 LMNA 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC155763 MAPT 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC169749 HSP90AB1 1 13500 IC50 PMID: 24548207
NPC179950 ALPL 1 14000 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC179950 KDM4E 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC18335 XDH 1 10890 IC50 PMID: 17379526
NPC194856 MMP1 1 11360 IC50 PMID: 22658537
NPC203468 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 ALDH1A1 2 Median: 15954.1
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 CA3 2 Median: 13000
Range: 13000 to 13000
Ki PMID: 18579385
PMID: 20185318
NPC204932 SMN1;SMN2 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 LMNA 2 Median: 23350.75
Range: 11220.2 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 HPGD 2 Median: 14501.5
Range: 11220.2 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 GMNN 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 CA4 3 Median: 10900
Range: 10900 to 10900
Ki PMID: 18579385
PMID: 20185318
PMID: 22245047
NPC20791 LMNA 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC20791 PIK3CG 1 13790 IC50 PMID: 25050878
NPC20791 PREP 1 13000 IC50 PMID: 18650094
NPC20791 LCK 2 Median: 13000
Range: 13000 to 13000
IC50 PMID: 1995903
PMID: 16441060
NPC20791 CALM1;CALM2;CALM3 1 12970 IC50 PMID: 21129983
NPC20791 PLAU 1 12100 IC50 PMID: 24610996
NPC20791 CA5B 1 11900 Ki PMID: 20185318
NPC20791 CYP2C19 1 10500 IC50 PMID: 22328583
NPC20791 MMP12 1 10230 IC50 PMID: 22658537
NPC20791 HIF1AN 1 10200 IC50 PMID: 19822432
NPC20791 CYP2C9 1 10200 IC50 PMID: 22328583
NPC219876 KDM4E 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 POLB 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 FUT4 1 14000 IC50 DOI: 10.1039/C4MD00086B
NPC23155 MAPK1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 KCNH2 1 10410 EC50 PubChem BioAssay data set
CHEMBL1201862
NPC264317 AKR1B1 1 11000 IC50 PMID: 21561086
NPC279121 MAPT 3 Median: 12589.3
Range: 12589.3 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC279121 SYK 1 12000 IC50 PMID: 22257213
NPC279121 HPGD 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC279121 MMP13 1 10050 IC50 PMID: 22658537
NPC294548 HSD17B10 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294902 THRB 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294902 CA4 1 10100 Ki PMID: 20185318
NPC29883 CA2 2 Median: 10600
Range: 10600 to 10600
Ki PMID: 18501600
PMID: 18579385
NPC306902 APAF1 1 10200 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC61477 MAPT 2 Median: 14125.4
Range: 14125.4 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC61477 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC61477 CA14 1 11550 Ki PMID: 20674354
NPC61477 KDM4E 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC61477 CA13 1 10510 Ki PMID: 20674354
NPC70744 CA3 1 11100 Ki PMID: 20185318
NPC70744 CA4 1 10800 Ki PMID: 20185318
NPC70744 CA5B 1 10500 Ki PMID: 20185318
NPC81010 HCAR2 1 14000 Ki PMID: 21167710
NPC85813 FABP4 2 Median: 15650
Range: 13600 to 17700
IC50 PMID: 20471252
PMID: 25461324
NPC85813 PTGS1 1 13000 IC50 PMID: 16038536
NPC9743 ALOX12 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC9743 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862