Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC142415 ACP1 4 Median: 22050
Range: 21200 to 22900
IC50 PMID: 21453996
PMID: 21453996
PMID: 25264584
PMID: 25264584
NPC142415 PTPN6 2 Median: 22760
Range: 14190 to 31330
IC50 PMID: 18707891
PMID: 27123900
NPC203719 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203719 ABAT 1 17100 IC50 PMID: 16290145
NPC203719 ALDH5A1 1 15600 IC50 PMID: 16290145
NPC203719 ALDH1A1 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC235059 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 AR 2 Median: 19027.305
Range: 19000 to 19054.61
IC50 PMID: 20226658
PMID: 20226658
NPC58616 ALDH1A1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87125 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC87125 TDP1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87125 KDM4E 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87125 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC93756 TP53 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC93756 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC93756 MAPT 3 Median: 28183.8
Range: 25118.9 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC99886 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99886 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC142415 PTPRF 2 Median: 17055
Range: 11800 to 22310
IC50 PMID: 21453996
PMID: 27123900
NPC142415 PTPN11 1 11620 IC50 PMID: 27123900
NPC234956 TDP1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 PTGS1 1 11000 IC50 PMID: 16038536
NPC87125 LMNA 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862