Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC191104 CYP2E1 1 40000 Ki PMID: 16248836
NPC191104 BACE1 1 32200 IC50 PMID: 22222157
NPC191104 CYP3A5 1 20000 Ki PMID: 16248836
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC250769 ALDH1A1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC88445 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC88445 LMNA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC191104 TSHR 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862