Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC103540 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 HPGD 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 TDP1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 ALOX15 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC254847 EPHX2 1 36400 IC50 PMID: 26483136
NPC254847 APEX1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC254847 TP53 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 PTP4A3 2 Median: 31500
Range: 28000 to 35000
IC50 PMID: 22137788
PMID: 22137788
NPC254847 NPC1 1 20596.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278175 ALOX12 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278175 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278175 ALOX15 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278175 USP2 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278175 CYP1A2 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC278175 ALDH1A1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278175 KDM4E 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 BRCA1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC282923 USP2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 KDM4E 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 TDP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 ELANE 1 18000 IC50 PMID: 1578486
NPC282923 TSHR 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC312929 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC312929 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC312929 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC3224 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC70622 EPHX2 1 26800 IC50 PMID: 26372074
NPC103540 HTT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC254847 TDP1 2 Median: 15186.05
Range: 12589.3 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 CYP2D6 2 Median: 22106.05
Range: 12589.3 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 THPO 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 GMNN 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC254847 ALDH1A1 2 Median: 13357.35
Range: 12589.3 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 MAPK1 2 Median: 11904.75
Range: 11220.2 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 POLB 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278175 TDP1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278175 TP53 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 ALDH1A1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC312929 HPGD 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC312929 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862