Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC119949 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC119949 SMN1;SMN2 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC201844 PPARA 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC201844 PPARD 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC201844 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC209970 ALOX15 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC209970 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC209970 TDP1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC209970 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC216630 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC261831 BLM 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 CYP19A1 1 32700 IC50 PMID: 16643058
NPC261831 TOP1 1 31000 IC50 PMID: 12444712
NPC261831 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 FABP4 1 26100 IC50 PMID: 20471252
NPC261831 KMT2A 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 ATM 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 HSD17B10 2 Median: 17900.75
Range: 15848.9 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294548 CYP19A1 1 44200 IC50 PMID: 16643058
NPC294548 BLM 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294548 L3MBTL1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294548 F3 1 30000 IC50 PMID: 9834151
NPC294548 HPGD 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294548 MAPT 3 Median: 28183.8
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294548 LMNA 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294548 PLA2G1B 1 22300 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC294548 KDM4E 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294548 PPARD 1 16000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC294548 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294548 ATG4B 1 15300 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC5989 MAPT 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85813 CYP19A1 1 48000 IC50 PMID: 16643058
NPC85813 F3 1 41000 IC50 PMID: 9834151
NPC85813 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85813 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85813 ALDH1A1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC201844 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 KCNH2 1 10410 EC50 PubChem BioAssay data set
CHEMBL1201862
NPC294548 HSD17B10 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85813 FABP4 2 Median: 15650
Range: 13600 to 17700
IC50 PMID: 20471252
PMID: 25461324
NPC85813 PTGS1 1 13000 IC50 PMID: 16038536