Plant ingredients against the target with activities between 10uM and 50uM
Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
---|---|---|---|---|---|
NPC137949 | GAA | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | ALDH1A1 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | HPGD | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | KDM4E | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | MAPT | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | CYP1A2 | 1 | 15848.93 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | GLA | 2 |
Median: 15954.1 Range: 14125.4 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC138113 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC139891 | TDP1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC13991 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC149184 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC149184 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC149184 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC155882 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC155882 | CYP3A4 | 1 | 24920 | IC50 |
PMID: 17400460 |
NPC155882 | MAPT | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC155882 | HPGD | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC171736 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC171736 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC171736 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC191104 | CYP2E1 | 1 | 40000 | Ki |
PMID: 16248836 |
NPC191104 | BACE1 | 1 | 32200 | IC50 |
PMID: 22222157 |
NPC191104 | CYP3A5 | 1 | 20000 | Ki |
PMID: 16248836 |
NPC194562 | CYP1A2 | 1 | 39810.72 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC194562 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC194562 | MAPK1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC194562 | CYP2C19 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC194562 | HPGD | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC201844 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC201844 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC201844 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC208936 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC208936 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC209970 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC209970 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC209970 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC209970 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC210460 | ABCB1 | 1 | 32000 | IC50 |
DOI: 10.1039/C4MD00196F |
NPC210460 | MAPT | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC221758 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
NPC243509 | BACE1 | 2 |
Median: 61150 Range: 30500 to 91800 |
IC50 |
PMID: 19939683 PMID: 22222157 |
NPC243509 | GAA | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC243509 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC243509 | ABCB1 | 1 | 28000 | IC50 |
DOI: 10.1039/C4MD00196F |
NPC247553 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC247553 | GAA | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC247553 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC247553 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC247553 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC247553 | AKR1B1 | 1 | 22900 | IC50 |
PMID: 20805028 |
NPC247553 | CASP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC247553 | CASP7 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC247553 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC250769 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC2518 | ATM | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC2518 | THRB | 2 |
Median: 34893.65 Range: 25118.9 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC261831 | BLM | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC261831 | CYP19A1 | 1 | 32700 | IC50 |
PMID: 16643058 |
NPC261831 | TOP1 | 1 | 31000 | IC50 |
PMID: 12444712 |
NPC261831 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC261831 | FABP4 | 1 | 26100 | IC50 |
PMID: 20471252 |
NPC261831 | KMT2A | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC261831 | ATM | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC261831 | HSD17B10 | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC278010 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC278010 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC279026 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC279026 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC279026 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC279026 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC296377 | GAA | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC296377 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC296377 | L3MBTL1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC296377 | ALDH1A1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC301585 | PPARD | 1 | 24000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC301585 | PPARG | 1 | 21000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC301696 | ALDH1A1 | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC310373 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC310373 | HPGD | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC310373 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC310373 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC33986 | GAA | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC33986 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC33986 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC51329 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC74539 | KDM4E | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC74539 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC74539 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC76336 | GLA | 2 |
Median: 40074.85 Range: 35481.3 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC76336 | GAA | 2 |
Median: 40074.85 Range: 35481.3 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC76336 | RECQL | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC76336 | CA13 | 1 | 17800 | Ki |
PMID: 22892213 |
NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
NPC85813 | CYP19A1 | 1 | 48000 | IC50 |
PMID: 16643058 |
NPC85813 | F3 | 1 | 41000 | IC50 |
PMID: 9834151 |
NPC85813 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC85813 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC85813 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC85813 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC88445 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC88445 | LMNA | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | HSD17B10 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC137949 | SMN1;SMN2 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC155882 | CYP2A6 | 1 | 11600 | Ki |
PMID: 16248836 |
NPC187145 | NPSR1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC191104 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC194562 | KDM4E | 3 |
Median: 28183.8 Range: 12589.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC201844 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC261831 | KCNH2 | 1 | 10410 | EC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |
NPC74539 | MAOA | 1 | 13800 | IC50 |
PMID: 23517722 |
NPC74539 | CYP2A6 | 1 | 12000 | Ki |
PMID: 16248836 |
NPC76336 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC76336 | CA1 | 1 | 10560 | Ki |
PMID: 22892213 |
NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |
NPC85813 | FABP4 | 2 |
Median: 15650 Range: 13600 to 17700 |
IC50 |
PMID: 20471252 PMID: 25461324 |
NPC85813 | PTGS1 | 1 | 13000 | IC50 |
PMID: 16038536 |