Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC133671 P4HB 1 19020 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC179950 EPHX2 1 28430 IC50 PMID: 24679441
NPC179950 XDH 1 26310 IC50 PMID: 12444671
NPC179950 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC209560 HSD17B10 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC209560 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC209560 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC209560 HPGD 2 Median: 30300.1
Range: 25118.9 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC209560 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 PMP22 1 47754.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234560 AKR1B10 1 32200 IC50 PMID: 26529431
NPC234560 HSD17B10 3 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 ALDH1A1 7 Median: 35481.3
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 PKM 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 KDM4E 4 Median: 29903.3
Range: 19952.6 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC234560 CYP3A4 4 Median: 20483.9
Range: 15848.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC234560 CYP2D6 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234560 HPGD 4 Median: 28370.85
Range: 14125.4 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC246162 APP 1 33000 IC50 PMID: 26719209
NPC246162 BACE1 2 Median: 32500
Range: 30000 to 35000
IC50 PMID: 14592472
PMID: 14592472
NPC246162 RECQL 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC246162 KDM4E 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC246162 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC246162 KIT 2 Median: 18800
Range: 15700 to 21900
IC50 PMID: 26807861
PMID: 26807861
NPC70622 EPHX2 1 26800 IC50 PMID: 26372074
NPC80710 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC80710 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC80710 POLB 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC179950 ALPL 1 14000 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC179950 KDM4E 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC192638 TOP2A 1 10400 IC50 PMID: 11754608
NPC209560 SMN1;SMN2 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234560 SMN1;SMN2 4 Median: 22016.35
Range: 12589.3 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294852 CYP1A1 1 10973 IC50 PMID: 20696580