Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC127447 | TSHR | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC236769 | ABCC1 | 1 | 50000 | IC50 |
PMID: 21354800 |
| NPC236769 | ABCB1 | 1 | 16000 | IC50 |
PMID: 21354800 |
| NPC242895 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | SLC16A3 | 1 | 41000 | IC50 |
PMID: 11101640 |
| NPC242895 | SLC28A3 | 1 | 32280 | Ki |
PMID: 19097778 |
| NPC242895 | TP53 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | MAPK1 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | KMT2A | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | GAA | 1 | 31381.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | KDM4E | 3 |
Median: 31622.8 Range: 28183.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | ALDH1A1 | 2 |
Median: 33997.25 Range: 28183.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | ATM | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | HPGD | 3 |
Median: 31622.8 Range: 25118.9 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | CYP2D6 | 2 |
Median: 32464.8 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | TDP1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | SLC2A1 | 1 | 21400 | IC50 |
PMID: 24200808 |
| NPC242895 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
| NPC247553 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | GAA | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | AKR1B1 | 1 | 22900 | IC50 |
PMID: 20805028 |
| NPC247553 | CASP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | CASP7 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC247553 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC263670 | DPP4 | 1 | 33110 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC278556 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC278556 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | MAPT | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | LMNA | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | EPHX2 | 1 | 21760 | IC50 |
PMID: 24679441 |
| NPC310259 | KDM4E | 2 |
Median: 33552.05 Range: 31622.8 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC310259 | ABCC1 | 1 | 26350 | IC50 |
PMID: 23851114 |
| NPC310259 | ABCB1 | 1 | 23400 | IC50 |
PMID: 23851114 |
| NPC310259 | ALDH1A1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC51700 | PPARA | 1 | 41310 | EC50 |
PMID: 21855333 |
| NPC51700 | AKR1B1 | 1 | 41000 | IC50 |
PMID: 21561086 |
| NPC51700 | CYP19A1 | 1 | 32000 | IC50 |
PMID: 18192087 |
| NPC51700 | PTPN6 | 1 | 25780 | IC50 |
PMID: 18707891 |
| NPC51700 | POLB | 1 | 18600 | IC50 |
PMID: 15165161 |
| NPC51700 | CTSD | 1 | 18200 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
| NPC51700 | SLCO1B1 | 1 | 15848.93 | IC50 |
PMID: 23571415 |
| NPC87231 | MAPT | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC99240 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC99240 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | HSD17B10 | 2 |
Median: 18854.1 Range: 12589.3 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | MAPT | 4 |
Median: 14219.1 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC242895 | RECQL | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC51700 | SLCO1B3 | 1 | 11481.54 | IC50 |
PMID: 23571415 |
| NPC87231 | NPSR1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC99240 | TP53 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC99240 | HPGD | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |