Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC110899 CA5B 1 35400 Ki PMID: 20185318
NPC191146 RELA 1 19000 IC50 PMID: 19839614
NPC254847 EPHX2 1 36400 IC50 PMID: 26483136
NPC254847 APEX1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC254847 TP53 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 PTP4A3 2 Median: 31500
Range: 28000 to 35000
IC50 PMID: 22137788
PMID: 22137788
NPC254847 NPC1 1 20596.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 BRCA1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC282923 USP2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 KDM4E 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 TDP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 ELANE 1 18000 IC50 PMID: 1578486
NPC282923 TSHR 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC312929 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC312929 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC312929 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC32441 GSK3B 1 45700 IC50 DOI: 10.1007/s00044-012-0353-y
NPC32441 AKR1B1 1 28870 IC50 PMID: 22261024
NPC32441 CYP1A2 1 26339 IC50 PMID: 20696580
NPC32441 CALM1;CALM2;CALM3 1 22010 IC50 PMID: 21129983
NPC32441 CBR1 1 21480 IC50 PMID: 19097799
NPC32441 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC32441 CYP1A1 1 15167 IC50 PMID: 20696580
NPC32441 HSD17B2 1 14400 IC50 PMID: 18533708
NPC70622 EPHX2 1 26800 IC50 PMID: 26372074
NPC110899 CA4 1 10600 Ki PMID: 20185318
NPC254847 TDP1 2 Median: 15186.05
Range: 12589.3 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 CYP2D6 2 Median: 22106.05
Range: 12589.3 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 THPO 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 GMNN 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC254847 ALDH1A1 2 Median: 13357.35
Range: 12589.3 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 MAPK1 2 Median: 11904.75
Range: 11220.2 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC254847 POLB 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282923 ALDH1A1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC312929 HPGD 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC312929 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC32441 ESR2 1 13473 IC50 PMID: 17149865
NPC32441 CYP2C9 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC33051 RELA 1 11300 IC50 PMID: 19839614