Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC142415 ACP1 4 Median: 22050
Range: 21200 to 22900
IC50 PMID: 21453996
PMID: 21453996
PMID: 25264584
PMID: 25264584
NPC142415 PTPN6 2 Median: 22760
Range: 14190 to 31330
IC50 PMID: 18707891
PMID: 27123900
NPC51700 PPARA 1 41310 EC50 PMID: 21855333
NPC51700 AKR1B1 1 41000 IC50 PMID: 21561086
NPC51700 CYP19A1 1 32000 IC50 PMID: 18192087
NPC51700 PTPN6 1 25780 IC50 PMID: 18707891
NPC51700 POLB 1 18600 IC50 PMID: 15165161
NPC51700 CTSD 1 18200 IC50 DOI: 10.1007/s00044-012-0397-z
NPC51700 SLCO1B1 1 15848.93 IC50 PMID: 23571415
NPC71074 PTPN6 1 24560 IC50 PMID: 18707891
NPC71074 PYGM 1 20000 IC50 PMID: 16169219
NPC84319 PYGM 1 28000 IC50 PMID: 16169219
NPC84319 PTPN2 1 19470 IC50 PMID: 19846303
NPC142415 PTPRF 2 Median: 17055
Range: 11800 to 22310
IC50 PMID: 21453996
PMID: 27123900
NPC142415 PTPN11 1 11620 IC50 PMID: 27123900
NPC192638 TOP2A 1 10400 IC50 PMID: 11754608
NPC51700 SLCO1B3 1 11481.54 IC50 PMID: 23571415
NPC71074 POLB 1 12600 IC50 PMID: 15165161
NPC71074 HTT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC71074 PTPN2 1 11310 IC50 PMID: 18707891