Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC14353 FASN 1 24830 IC50 PMID: 20817450
NPC228785 CYP3A4 4 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 TP53 3 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 CYP2D6 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 KDM4E 2 Median: 32464.8
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 CYP19A1 1 20700 IC50 PMID: 18558747
NPC228785 HPGD 2 Median: 24068.2
Range: 19952.6 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 MAPK1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 RELA 1 15900 IC50 PMID: 19839614
NPC275780 FASN 1 40640 IC50 PMID: 20817450
NPC51700 PPARA 1 41310 EC50 PMID: 21855333
NPC51700 AKR1B1 1 41000 IC50 PMID: 21561086
NPC51700 CYP19A1 1 32000 IC50 PMID: 18192087
NPC51700 PTPN6 1 25780 IC50 PMID: 18707891
NPC51700 POLB 1 18600 IC50 PMID: 15165161
NPC51700 CTSD 1 18200 IC50 DOI: 10.1007/s00044-012-0397-z
NPC51700 SLCO1B1 1 15848.93 IC50 PMID: 23571415
NPC14353 RELA 1 12100 IC50 PMID: 19839614
NPC14353 IDH1 1 12000 Ki PMID: 26508549
NPC51700 SLCO1B3 1 11481.54 IC50 PMID: 23571415