Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC14353 FASN 1 24830 IC50 PMID: 20817450
NPC188433 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188433 SMN1;SMN2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC188433 MAPT 3 Median: 22387.2
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 CYP3A4 4 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 TP53 3 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 CYP2D6 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 KDM4E 2 Median: 32464.8
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 CYP19A1 1 20700 IC50 PMID: 18558747
NPC228785 HPGD 2 Median: 24068.2
Range: 19952.6 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC228785 MAPK1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC228785 RELA 1 15900 IC50 PMID: 19839614
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC14353 RELA 1 12100 IC50 PMID: 19839614
NPC14353 IDH1 1 12000 Ki PMID: 26508549