Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC110899 CA5B 1 35400 Ki PMID: 20185318
NPC121510 CDK2 1 15000 IC50 PMID: 20097066
NPC163984 ALDH1A1 2 Median: 25285.5
Range: 22387.2 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC171882 CDK2 1 30000 IC50 PMID: 20097066
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC240684 CDK2 1 25000 IC50 PMID: 20097066
NPC287331 RECQL 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC287331 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC287331 TSHR 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC317145 TDP1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC69213 CDK2 1 15000 IC50 PMID: 20097066
NPC81010 ESR1 1 16120 EC50 PMID: 23608764
NPC85661 ALDH1A1 2 Median: 42239.55
Range: 39810.7 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC91234 CDK2 1 25000 IC50 PMID: 20097066
NPC110899 CA4 1 10600 Ki PMID: 20185318
NPC153556 RGS12 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC81010 HCAR2 1 14000 Ki PMID: 21167710
NPC85661 MAPT 3 Median: 14125.4
Range: 12589.3 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862