Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC146976 L3MBTL1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC146976 APAF1 1 24400 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC146976 PPP5C 1 19597 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC193949 APAF1 1 16300 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC193949 L3MBTL1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC195268 ALOX15 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC195268 ACHE 1 24330 IC50 PMID: 16483771
NPC202771 SLC47A1 1 34500 IC50 PMID: 23241029
NPC202771 MAPK1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC202771 CYP1A2 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC219913 ALDH5A1 1 24700 IC50 PMID: 16290145
NPC219913 ABAT 1 16500 IC50 PMID: 16290145
NPC224651 EGLN1 2 Median: 119500
Range: 19000 to 220000
IC50 PMID: 18942826
PMID: 23234607
NPC232533 SLC22A1 1 28000 IC50 PMID: 18788725
NPC233780 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC249797 CYP1A2 1 15848.93 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC249797 CASP1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC255607 OPRM1 1 32500 EC50 PMID: 17616524
NPC282895 ALOX15 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC282895 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC303581 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC308267 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC308267 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC43069 OPRK1 1 15000 IC50 PMID: 12502358
NPC46451 RAB9A 1 46109.1 Potency PubChem BioAssay data set
CHEMBL1201862
NPC46451 RGS12 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC46451 MAPK1 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 USP2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC46451 ALDH1A1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC46451 BAD 1 19000 IC50 PMID: 18925736
NPC46451 MAPT 2 Median: 22983.3
Range: 17782.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 CYP2C9 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC81010 ESR1 1 16120 EC50 PMID: 23608764
NPC195268 CYP2C9 2 Median: 26200
Range: 12589.3 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC195268 THPO 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC195268 USP2 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC249797 KDM4E 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC249797 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC293378 ALDH1A1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC29883 CA2 2 Median: 10600
Range: 10600 to 10600
Ki PMID: 18501600
PMID: 18579385
NPC308267 TSHR 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 HPGD 2 Median: 21154.6
Range: 14125.4 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 TSHR 4 Median: 18854.1
Range: 12589.3 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC46451 SMN1;SMN2 2 Median: 16803.7
Range: 11220.2 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC81010 HCAR2 1 14000 Ki PMID: 21167710