Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC107482 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC1075 | CYP2C9 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC139416 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC139416 | CYP2A6 | 2 |
Median: 33981.265 Range: 33962.53 to 34000 |
IC50 |
PMID: 15658857 PMID: 19110342 |
| NPC139548 | CA7 | 1 | 23800 | Ki |
PMID: 22892213 |
| NPC142319 | TYR | 2 |
Median: 130130 Range: 30260 to 230000 |
IC50 |
PMID: 16872137 PMID: 17693086 |
| NPC149184 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC163556 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC163556 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC17810 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC17810 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC181465 | XDH | 1 | 14800 | IC50 |
PMID: 9461655 |
| NPC18188 | SLC6A12 | 1 | 36000 | IC50 |
PMID: 8057281 |
| NPC18188 | NPSR1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18188 | TSHR | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18188 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18188 | THRB | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC209970 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC217226 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC231772 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | TP53 | 2 |
Median: 28370.85 Range: 25118.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
| NPC265885 | RECQL | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC265885 | GAA | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC265885 | L3MBTL1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC291066 | ALOX12 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC291066 | CYP2A6 | 2 |
Median: 25001.725 Range: 25000 to 25003.45 |
IC50 |
PMID: 15658857 PMID: 19110342 |
| NPC294548 | CYP19A1 | 1 | 44200 | IC50 |
PMID: 16643058 |
| NPC294548 | BLM | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | L3MBTL1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | F3 | 1 | 30000 | IC50 |
PMID: 9834151 |
| NPC294548 | HPGD | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | MAPT | 3 |
Median: 28183.8 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | LMNA | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | PLA2G1B | 1 | 22300 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | KDM4E | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | PPARD | 1 | 16000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC294548 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | ATG4B | 1 | 15300 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | HPGD | 3 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APP | 1 | 32800 | IC50 |
PMID: 22921742 |
| NPC294902 | AKR1B1 | 1 | 32000 | IC50 |
PMID: 22236472 |
| NPC294902 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | POLB | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC300059 | CYP2C19 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC300059 | LMNA | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC301585 | PPARD | 1 | 24000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC301585 | PPARG | 1 | 21000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC306397 | SIRT5 | 1 | 46600 | IC50 |
PMID: 24900427 |
| NPC306397 | SIRT1 | 7 |
Median: 73000 Range: 25000 to 149000 |
IC50 |
PMID: 19700324 PMID: 23318905 PMID: 24900427 PMID: 25275824 PMID: 25549554 PMID: 26696402 DOI: 10.1039/C1MD00199J |
| NPC50898 | APEX1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | THRB | 2 |
Median: 44964.7 Range: 39810.7 to 50118.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | BACE1 | 2 |
Median: 38500 Range: 38500 to 38500 |
IC50 |
PMID: 22243648 DOI: 10.1007/s00044-012-0353-y |
| NPC50898 | BCHE | 1 | 37400 | Ki |
PMID: 19879672 |
| NPC50898 | HBB | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | DAPK1 | 1 | 31000 | IC50 |
PMID: 26322379 |
| NPC50898 | NPSR1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | HPGD | 3 |
Median: 28183.8 Range: 22387.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | NFKB1 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | MAPK1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC76336 | GLA | 2 |
Median: 40074.85 Range: 35481.3 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC76336 | GAA | 2 |
Median: 40074.85 Range: 35481.3 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC76336 | RECQL | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC76336 | CA13 | 1 | 17800 | Ki |
PMID: 22892213 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC84281 | KDM4E | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC84281 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP19A1 | 1 | 48000 | IC50 |
PMID: 16643058 |
| NPC85813 | F3 | 1 | 41000 | IC50 |
PMID: 9834151 |
| NPC85813 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC1075 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC139548 | CA1 | 1 | 14000 | Ki |
PMID: 22892213 |
| NPC231772 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | SMN1;SMN2 | 2 |
Median: 19622.15 Range: 14125.4 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | USP2 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | CYP2D6 | 1 | 12589.25 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | HSD17B10 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | THRB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | CA4 | 1 | 10100 | Ki |
PMID: 20185318 |
| NPC50898 | SMN1;SMN2 | 5 |
Median: 22387.2 Range: 14125.4 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | MAOB | 1 | 12800 | IC50 |
PMID: 20045650 |
| NPC50898 | CYP2D6 | 2 |
Median: 26200 Range: 12589.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | LMNA | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | AKR1B1 | 1 | 11900 | IC50 |
PMID: 26529431 |
| NPC50898 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
| NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
| NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |
| NPC76336 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC76336 | CA1 | 1 | 10560 | Ki |
PMID: 22892213 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |
| NPC85813 | FABP4 | 2 |
Median: 15650 Range: 13600 to 17700 |
IC50 |
PMID: 20471252 PMID: 25461324 |
| NPC85813 | PTGS1 | 1 | 13000 | IC50 |
PMID: 16038536 |