Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC107572 PDE5A 1 16230 IC50 PMID: 18778098
NPC115159 TP53 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC115159 ALOX15 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC115159 CYP2C9 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC115159 PKM 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC115159 CYP2D6 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC178014 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC19174 BACE1 1 33000 IC50 DOI: 10.1007/s00044-012-0353-y
NPC19174 NPSR1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 KMT2A 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 MTOR 1 26121.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 APP 1 19700 IC50 PMID: 23786711
NPC19174 GMNN 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC19174 PMP22 1 15101.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC259767 DPP4 1 26920 IC50 DOI: 10.1039/C0MD00245C
NPC115159 CYP2C19 1 12589.25 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC19174 CHRNA7 1 11600 EC50 PMID: 25232969