Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC100551 CA14 1 49800 Ki PMID: 18579385
NPC100551 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100551 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100551 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100551 HPGD 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110126 CYP2C19 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110126 HSD17B10 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110126 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110126 TSHR 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110126 ALDH1A1 2 Median: 27829.8
Range: 15848.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC125732 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC125732 CYP2C19 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC125732 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC125732 HTR3A 1 26000 EC50 PMID: 18033297
NPC167400 ALDH1A1 1 18029.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC207554 KMT2A 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC207554 MAPT 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC27633 ESR1 1 38200 EC50 PMID: 23608764
NPC309330 NFKB1 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC3343 SRR 2 Median: 667450
Range: 24900 to 1310000
IC50 PMID: 23391306
PMID: 25066953
NPC60120 AKR1C4 1 37000 Ki PMID: 22877157
NPC60120 AKR1C2 1 18000 Ki PMID: 22877157
NPC96102 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC96102 CYP2D6 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC96102 CYP2A13 1 16000 Ki PMID: 22696418
NPC96102 CTSK 1 15000 IC50 PMID: 11975521
NPC100551 CA6 2 Median: 1165950
Range: 11900 to 2320000
Ki PMID: 18579385
PMID: 21669522
NPC100551 CA4 1 11100 Ki PMID: 18579385
NPC125732 L3MBTL1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC207554 HTT 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC96102 NFKB1 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862