Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC144939 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC144939 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC289774 TDP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294941 ALOX15 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294941 KDM4E 3 Median: 35481.3
Range: 28183.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294941 MAPK1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294941 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294941 ALDH1A1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294941 HPGD 2 Median: 21169.9
Range: 19952.6 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC300326 PTGS1 1 39200 IC50 PMID: 22386242
NPC300326 PTGS2 1 28000 IC50 PMID: 22386242
NPC70744 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC81010 ESR1 1 16120 EC50 PMID: 23608764
NPC12278 ALOX5 1 13000 IC50 PMID: 24568174
NPC156018 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC25496 POLB 1 12300 IC50 PMID: 15217274
NPC70744 CA3 1 11100 Ki PMID: 20185318
NPC70744 CA4 1 10800 Ki PMID: 20185318
NPC70744 CA5B 1 10500 Ki PMID: 20185318
NPC81010 HCAR2 1 14000 Ki PMID: 21167710