Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC152771 ALDH1A1 1 39810.7 Potency PMID: 23411072
NPC152771 KDM4E 1 31622.8 Potency PMID: 23891163
NPC152771 RCE1 1 24940 AC50 PMID: 26636180
NPC152771 HPGD 1 15848.9 Potency PMID: 18710917
NPC168799 MMP13 1 29030 IC50 PMID: 22658537
NPC168799 MMP3 1 28260 IC50 PMID: 22658537
NPC168799 MMP1 2 Median: 14720
Range: 14700 to 14740
IC50 PMID: 22658537
PMID: 23353736
NPC173637 PIM2 1 25000 IC50 PMID: 18163587
NPC173637 L3MBTL1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC173637 XDH 1 14740 IC50 PMID: 12444671
NPC234536 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 POLB 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC266689 LMNA 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 MAPT 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 LMNA 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 EPHX2 1 21760 IC50 PMID: 24679441
NPC33320 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC38473 SRC 1 36200 IC50 PMID: 19427202
NPC38473 LCK 1 23500 IC50 PMID: 19427202
NPC475042 CASP3 1 28100 IC50 PMID: 20566771
NPC72158 PTPN1 1 27300 IC50 PMID: 24047800
NPC74539 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC74539 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC74539 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC166934 ABCG2 1 12300 IC50 PMID: 21275386
NPC168105 LMNA 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC168105 MAPT 3 Median: 15848.9
Range: 11220.2 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC33320 CYP3A4 4 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC74539 MAOA 1 13800 IC50 PMID: 23517722
NPC74539 CYP2A6 1 12000 Ki PMID: 16248836