Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC100887 AMY1A;AMY1B;AMY1C 1 48000 IC50 PMID: 18507367
NPC100887 BLM 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100887 MAPT 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC116775 BCHE 1 43100 Ki PMID: 19879672
NPC116775 ALDH1A1 2 Median: 35716.75
Range: 31622.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC116775 CDK6 2 Median: 22000
Range: 22000 to 22000
IC50 PMID: 15689157
DOI: 10.1007/s00044-009-9233-5
NPC116775 GLO1 1 20600 IC50 PMID: 18258440
NPC116775 KDM4E 2 Median: 27829.8
Range: 15848.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 HSD17B10 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 BACE1 1 14700 IC50 DOI: 10.1007/s00044-012-0353-y
NPC167400 ALDH1A1 1 18029.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC241498 ATM 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC241498 TDP1 2 Median: 46590.9
Range: 22387.2 to 70794.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC241498 MAPT 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC75906 PTGS1 1 40000 IC50 PMID: 16038536
NPC116775 MAPT 2 Median: 14219.1
Range: 12589.3 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862