Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC110899 CA5B 1 35400 Ki PMID: 20185318
NPC217176 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC236769 ABCC1 1 50000 IC50 PMID: 21354800
NPC236769 ABCB1 1 16000 IC50 PMID: 21354800
NPC270620 ABCC1 1 50000 IC50 PMID: 21354800
NPC34770 ALDH1A1 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 TP53 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC34770 CYP2D6 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC78326 ABCG2 1 17200 IC50 PMID: 21275386
NPC96286 ALOX5 1 36200 IC50 PMID: 9544564
NPC96286 ABCB1 1 34000 IC50 DOI: 10.1039/C4MD00196F
NPC96286 ALDH1A1 2 Median: 36426.1
Range: 28183.8 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC96286 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110899 CA4 1 10600 Ki PMID: 20185318
NPC270620 ABCB1 1 13000 IC50 PMID: 21354800
NPC34770 HPGD 2 Median: 14125.4
Range: 14125.4 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 HSD17B10 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC34770 KDM4E 2 Median: 13357.35
Range: 12589.3 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862