Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC19890 CYP2D6 1 26500 IC50 PMID: 15679319
NPC19890 SLC6A1 1 20600 IC50 PMID: 24112084
NPC237946 ALDH1A1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 MAPT 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 HSD17B10 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC257188 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 CA12 1 25700 Ki PMID: 22892213
NPC257188 CA1 1 21500 Ki PMID: 22892213
NPC257188 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85233 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85233 ALDH1A1 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85233 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85233 MAPT 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85233 KDM4E 3 Median: 25118.9
Range: 22387.2 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC85233 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC85233 ABCB1 1 11500 IC50 PMID: 11743742
NPC85233 MAPK1 2 Median: 21421.5
Range: 11220.2 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862