Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC113733 | POLB | 2 |
Median: 51840 Range: 43400 to 60280 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC234536 | HPGD | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC234536 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC234536 | POLB | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC243509 | BACE1 | 2 |
Median: 61150 Range: 30500 to 91800 |
IC50 |
PMID: 19939683 PMID: 22222157 |
| NPC243509 | GAA | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC243509 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC243509 | ABCB1 | 1 | 28000 | IC50 |
DOI: 10.1039/C4MD00196F |
| NPC74539 | KDM4E | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC74539 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC74539 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC96286 | ALOX5 | 1 | 36200 | IC50 |
PMID: 9544564 |
| NPC96286 | ABCB1 | 1 | 34000 | IC50 |
DOI: 10.1039/C4MD00196F |
| NPC96286 | ALDH1A1 | 2 |
Median: 36426.1 Range: 28183.8 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC96286 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC192638 | TOP2A | 1 | 10400 | IC50 |
PMID: 11754608 |
| NPC74539 | MAOA | 1 | 13800 | IC50 |
PMID: 23517722 |
| NPC74539 | CYP2A6 | 1 | 12000 | Ki |
PMID: 16248836 |