Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC107482 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 MAPK1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110396 SMN1;SMN2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 KDM4E 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 TP53 2 Median: 23735.85
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110899 CA5B 1 35400 Ki PMID: 20185318
NPC113733 POLB 2 Median: 51840
Range: 43400 to 60280
IC50 PMID: 14640519
PMID: 18343122
NPC117237 ALDH1A1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC117237 AOX1 1 15000 IC50 PMID: 20853847
NPC141765 PPARD 1 18110 EC50 PMID: 27450788
NPC141765 PTPN1 1 15010 IC50 PMID: 24224843
NPC161187 PTPN1 1 20200 IC50 PMID: 16545563
NPC167400 ALDH1A1 1 18029.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC184026 DRD1 1 21270 IC50 PMID: 23332346
NPC184026 DRD2 1 18730 IC50 PMID: 23332346
NPC189470 PTPRCAP 1 17000 IC50 DOI: 10.1016/0960-894X(95)00250-W
NPC203719 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203719 ABAT 1 17100 IC50 PMID: 16290145
NPC203719 ALDH5A1 1 15600 IC50 PMID: 16290145
NPC203719 ALDH1A1 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC205421 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC205421 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219913 ALDH5A1 1 24700 IC50 PMID: 16290145
NPC219913 ABAT 1 16500 IC50 PMID: 16290145
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC24019 CYP2C9 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 CASP1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 MAPK1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 KMT2A 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 KDM4E 2 Median: 19118.05
Range: 15848.9 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC43246 SLC28A2 1 32000 IC50 PMID: 23388705
NPC70744 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110899 CA4 1 10600 Ki PMID: 20185318
NPC205421 CYP2C9 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC205421 KDM4E 2 Median: 24035.3
Range: 12589.3 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC24019 CYP2C19 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC24019 POLB 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC29883 CA2 2 Median: 10600
Range: 10600 to 10600
Ki PMID: 18501600
PMID: 18579385
NPC70744 CA3 1 11100 Ki PMID: 20185318
NPC70744 CA4 1 10800 Ki PMID: 20185318
NPC70744 CA5B 1 10500 Ki PMID: 20185318