Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC101475 AKR1B10 1 30000 IC50 PMID: 21561086
NPC141765 PPARD 1 18110 EC50 PMID: 27450788
NPC141765 PTPN1 1 15010 IC50 PMID: 24224843
NPC142415 ACP1 4 Median: 22050
Range: 21200 to 22900
IC50 PMID: 21453996
PMID: 21453996
PMID: 25264584
PMID: 25264584
NPC142415 PTPN6 2 Median: 22760
Range: 14190 to 31330
IC50 PMID: 18707891
PMID: 27123900
NPC156461 GAPDH 7 Median: 35000000
Range: 35000 to 100000000
IC50 PMID: 7562915
PMID: 7562915
PMID: 7562915
PMID: 7932587
PMID: 7932587
PMID: 7932587
PMID: 9822549
NPC156461 ADORA2B 3 Median: 24000
Range: 24000 to 24000
EC50 PMID: 20541935
PMID: 21388809
PMID: 24164628
NPC156461 SLC29A1 1 17000 IC50 PMID: 23388705
NPC220498 GLI1 2 Median: 42000
Range: 42000 to 42000
IC50 PMID: 18842418
PMID: 19309080
NPC263548 AKR1B1 1 34000 IC50 PMID: 21561086
NPC267691 NOS2 1 37000 IC50 PMID: 15837296
NPC84319 PYGM 1 28000 IC50 PMID: 16169219
NPC84319 PTPN2 1 19470 IC50 PMID: 19846303
NPC142415 PTPRF 2 Median: 17055
Range: 11800 to 22310
IC50 PMID: 21453996
PMID: 27123900
NPC142415 PTPN11 1 11620 IC50 PMID: 27123900
NPC156461 MAPK1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862