Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC110396 MAPK1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC110396 SMN1;SMN2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 KDM4E 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC110396 TP53 2 Median: 23735.85
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC120537 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC120537 ALDH1A1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC120537 LMNA 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC120537 HPGD 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC163076 CA2 7 Median: 20000
Range: 20000 to 20000
Ki PMID: 15357993
PMID: 15454240
PMID: 15501038
PMID: 21208801
PMID: 26525863
PMID: 26853167
PMID: 27283786
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC278556 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278556 KDM4E 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC329203 ATM 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC329203 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC120537 MAPT 2 Median: 18854.1
Range: 12589.3 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862