Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC107482 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC1075 | CYP2C9 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | BCHE | 1 | 43100 | Ki |
PMID: 19879672 |
| NPC116775 | ALDH1A1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | CDK6 | 2 |
Median: 22000 Range: 22000 to 22000 |
IC50 |
PMID: 15689157 DOI: 10.1007/s00044-009-9233-5 |
| NPC116775 | GLO1 | 1 | 20600 | IC50 |
PMID: 18258440 |
| NPC116775 | KDM4E | 2 |
Median: 27829.8 Range: 15848.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | HSD17B10 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | BACE1 | 1 | 14700 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC119949 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC119949 | SMN1;SMN2 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC133671 | P4HB | 1 | 19020 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | GAA | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | ALDH1A1 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | HPGD | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | KDM4E | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | MAPT | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | CYP1A2 | 1 | 15848.93 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | GLA | 2 |
Median: 15954.1 Range: 14125.4 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC149184 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC156461 | GAPDH | 7 |
Median: 35000000 Range: 35000 to 100000000 |
IC50 |
PMID: 7562915 PMID: 7562915 PMID: 7562915 PMID: 7932587 PMID: 7932587 PMID: 7932587 PMID: 9822549 |
| NPC156461 | ADORA2B | 3 |
Median: 24000 Range: 24000 to 24000 |
EC50 |
PMID: 20541935 PMID: 21388809 PMID: 24164628 |
| NPC156461 | SLC29A1 | 1 | 17000 | IC50 |
PMID: 23388705 |
| NPC171736 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC171736 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC171736 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179092 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179092 | KDM4E | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179092 | F3 | 1 | 32000 | IC50 |
PMID: 9834151 |
| NPC179092 | MAPT | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | EPHX2 | 1 | 28430 | IC50 |
PMID: 24679441 |
| NPC179950 | XDH | 1 | 26310 | IC50 |
PMID: 12444671 |
| NPC179950 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC181465 | XDH | 1 | 14800 | IC50 |
PMID: 9461655 |
| NPC186098 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC186098 | HPGD | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC201844 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC201844 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC201844 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC20791 | PMP22 | 1 | 47754.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GALK1 | 1 | 42128.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK2 | 1 | 40000 | IC50 |
PMID: 17178224 |
| NPC20791 | CD38 | 1 | 37900 | IC50 |
PMID: 21641214 |
| NPC20791 | SORD | 2 |
Median: 106300 Range: 35600 to 177000 |
IC50 |
PMID: 8893834 PMID: 12672241 |
| NPC20791 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | EPHX2 | 1 | 33540 | IC50 |
PMID: 24679441 |
| NPC20791 | DPP4 | 2 |
Median: 81365 Range: 32730 to 130000 |
IC50 |
PMID: 18650094 DOI: 10.1039/C0MD00245C |
| NPC20791 | MAPK1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ADORA3 | 1 | 30000 | Ki |
PMID: 8576921 |
| NPC20791 | PTGS2 | 1 | 28600 | IC50 |
PMID: 17378609 |
| NPC20791 | BLM | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | TDP1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ALDH1A1 | 6 |
Median: 37646 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK6 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 15689157 DOI: 10.1007/s00044-009-9233-5 |
| NPC20791 | PTPN1 | 2 |
Median: 23300 Range: 23300 to 23300 |
IC50 |
PMID: 12419367 PMID: 19297174 |
| NPC20791 | KMT2A | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | AMY1A;AMY1B;AMY1C | 1 | 21400 | IC50 |
PMID: 18507367 |
| NPC20791 | SYK | 1 | 20000 | IC50 |
PMID: 22257213 |
| NPC20791 | HPGD | 2 |
Median: 21169.9 Range: 19952.6 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | APEX1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CYP2D6 | 1 | 18800 | IC50 |
PMID: 22328583 |
| NPC20791 | USP2 | 2 |
Median: 25057.75 Range: 18492.7 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GPR35 | 1 | 15400 | IC50 |
PMID: 24900447 |
| NPC20791 | APP | 1 | 15300 | IC50 |
PMID: 26719209 |
| NPC209970 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC209970 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC219913 | ALDH5A1 | 1 | 24700 | IC50 |
PMID: 16290145 |
| NPC219913 | ABAT | 1 | 16500 | IC50 |
PMID: 16290145 |
| NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
| NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
| NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
| NPC261831 | BLM | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | CYP19A1 | 1 | 32700 | IC50 |
PMID: 16643058 |
| NPC261831 | TOP1 | 1 | 31000 | IC50 |
PMID: 12444712 |
| NPC261831 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | FABP4 | 1 | 26100 | IC50 |
PMID: 20471252 |
| NPC261831 | KMT2A | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | ATM | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC261831 | HSD17B10 | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC265885 | RECQL | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC265885 | GAA | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC265885 | L3MBTL1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC270796 | CYP19A1 | 1 | 33200 | IC50 |
PMID: 16643058 |
| NPC270796 | ALDH1A1 | 2 |
Median: 22387.2 Range: 22387.2 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC287895 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287895 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | CYP19A1 | 1 | 44200 | IC50 |
PMID: 16643058 |
| NPC294548 | BLM | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | L3MBTL1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | F3 | 1 | 30000 | IC50 |
PMID: 9834151 |
| NPC294548 | HPGD | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | MAPT | 3 |
Median: 28183.8 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | LMNA | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | PLA2G1B | 1 | 22300 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | KDM4E | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | PPARD | 1 | 16000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC294548 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | ATG4B | 1 | 15300 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | HPGD | 3 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APP | 1 | 32800 | IC50 |
PMID: 22921742 |
| NPC294902 | AKR1B1 | 1 | 32000 | IC50 |
PMID: 22236472 |
| NPC294902 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | POLB | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC301585 | PPARD | 1 | 24000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC301585 | PPARG | 1 | 21000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC42372 | IMPDH2 | 1 | 22700 | IC50 |
PMID: 16483769 |
| NPC43246 | SLC28A2 | 1 | 32000 | IC50 |
PMID: 23388705 |
| NPC49074 | PTGS1 | 1 | 36000 | IC50 |
PMID: 16038536 |
| NPC6095 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC85813 | CYP19A1 | 1 | 48000 | IC50 |
PMID: 16643058 |
| NPC85813 | F3 | 1 | 41000 | IC50 |
PMID: 9834151 |
| NPC85813 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC85813 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC1075 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC116775 | MAPT | 2 |
Median: 14219.1 Range: 12589.3 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | HSD17B10 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | SMN1;SMN2 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156461 | MAPK1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | ALPL | 1 | 14000 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC18335 | XDH | 1 | 10890 | IC50 |
PMID: 17379526 |
| NPC201844 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | PIK3CG | 1 | 13790 | IC50 |
PMID: 25050878 |
| NPC20791 | PREP | 1 | 13000 | IC50 |
PMID: 18650094 |
| NPC20791 | LCK | 2 |
Median: 13000 Range: 13000 to 13000 |
IC50 |
PMID: 1995903 PMID: 16441060 |
| NPC20791 | CALM1;CALM2;CALM3 | 1 | 12970 | IC50 |
PMID: 21129983 |
| NPC20791 | PLAU | 1 | 12100 | IC50 |
PMID: 24610996 |
| NPC20791 | CA5B | 1 | 11900 | Ki |
PMID: 20185318 |
| NPC20791 | CYP2C19 | 1 | 10500 | IC50 |
PMID: 22328583 |
| NPC20791 | MMP12 | 1 | 10230 | IC50 |
PMID: 22658537 |
| NPC20791 | HIF1AN | 1 | 10200 | IC50 |
PMID: 19822432 |
| NPC20791 | CYP2C9 | 1 | 10200 | IC50 |
PMID: 22328583 |
| NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
| NPC261831 | KCNH2 | 1 | 10410 | EC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC270796 | FFAR1 | 2 |
Median: 23850 Range: 11700 to 36000 |
EC50 |
PMID: 24900539 PMID: 27326330 |
| NPC270796 | MAPT | 3 |
Median: 15848.9 Range: 11220.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294548 | HSD17B10 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | THRB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | CA4 | 1 | 10100 | Ki |
PMID: 20185318 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
| NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
| NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |
| NPC85813 | FABP4 | 2 |
Median: 15650 Range: 13600 to 17700 |
IC50 |
PMID: 20471252 PMID: 25461324 |
| NPC85813 | PTGS1 | 1 | 13000 | IC50 |
PMID: 16038536 |