Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC138299 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC138299 PLCG1 1 29000 IC50 PMID: 10869194
NPC138299 PLA2G2A 1 23800 IC50 PMID: 16504502
NPC138299 HPGD 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC208553 CYP1A2 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC208553 ABCB11 2 Median: 27850
Range: 26800 to 28900
IC50 PMID: 12739759
PMID: 12739759
NPC208553 CYP2C9 1 25118.86 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC208553 FYN 1 23906 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC208553 MAPT 2 Median: 33527.8
Range: 22387.2 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC208553 BLM 2 Median: 17782.8
Range: 17782.8 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC208553 MC5R 1 17133 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC208553 HIF1A 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC208553 RECQL 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219913 ALDH5A1 1 24700 IC50 PMID: 16290145
NPC219913 ABAT 1 16500 IC50 PMID: 16290145
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC286006 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC208553 THPO 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC208553 NPSR1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC208553 CCKAR 1 11380 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC208553 ERBB2 1 11108 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046