Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC131530 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156461 | GAPDH | 7 |
Median: 35000000 Range: 35000 to 100000000 |
IC50 |
PMID: 7562915 PMID: 7562915 PMID: 7562915 PMID: 7932587 PMID: 7932587 PMID: 7932587 PMID: 9822549 |
| NPC156461 | ADORA2B | 3 |
Median: 24000 Range: 24000 to 24000 |
EC50 |
PMID: 20541935 PMID: 21388809 PMID: 24164628 |
| NPC156461 | SLC29A1 | 1 | 17000 | IC50 |
PMID: 23388705 |
| NPC156654 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | CYP2C9 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | CYP2C19 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | THRB | 2 |
Median: 32464.8 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | CARM1 | 1 | 25000 | IC50 |
DOI: 10.1039/C1MD00199J |
| NPC178134 | GSR | 1 | 22800 | IC50 |
PMID: 19015351 |
| NPC178134 | EPHX2 | 1 | 20700 | IC50 |
PMID: 24679441 |
| NPC178134 | ATM | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | MAPK1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | HPGD | 3 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | APP | 1 | 32800 | IC50 |
PMID: 22921742 |
| NPC294902 | AKR1B1 | 1 | 32000 | IC50 |
PMID: 22236472 |
| NPC294902 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | POLB | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61 | SRC | 1 | 26000 | IC50 |
PMID: 19427202 |
| NPC61 | THRB | 2 |
Median: 34893.65 Range: 25118.9 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC61 | USP2 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61 | LCK | 2 |
Median: 39500 Range: 24000 to 55000 |
IC50 |
PMID: 14505648 PMID: 19427202 |
| NPC61 | BLM | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC61 | JUN | 1 | 16200 | IC50 |
PMID: 24491635 |
| NPC61 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC131530 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC131530 | MAPT | 2 |
Median: 12672.8 Range: 11220.2 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC156461 | MAPK1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | CA5B | 1 | 12700 | Ki |
PMID: 20185318 |
| NPC178134 | MAPT | 8 |
Median: 21169.9 Range: 12589.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | TP53 | 2 |
Median: 22106.05 Range: 12589.3 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | KMT2A | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC178134 | CA3 | 1 | 10500 | Ki |
PMID: 20185318 |
| NPC294902 | THRB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294902 | CA4 | 1 | 10100 | Ki |
PMID: 20185318 |
| NPC61 | MAPT | 3 |
Median: 14125.4 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |