Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC110899 | CA5B | 1 | 35400 | Ki |
PMID: 20185318 |
| NPC138299 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC138299 | PLCG1 | 1 | 29000 | IC50 |
PMID: 10869194 |
| NPC138299 | PLA2G2A | 1 | 23800 | IC50 |
PMID: 16504502 |
| NPC138299 | HPGD | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC141765 | PPARD | 1 | 18110 | EC50 |
PMID: 27450788 |
| NPC141765 | PTPN1 | 1 | 15010 | IC50 |
PMID: 24224843 |
| NPC156461 | GAPDH | 7 |
Median: 35000000 Range: 35000 to 100000000 |
IC50 |
PMID: 7562915 PMID: 7562915 PMID: 7562915 PMID: 7932587 PMID: 7932587 PMID: 7932587 PMID: 9822549 |
| NPC156461 | ADORA2B | 3 |
Median: 24000 Range: 24000 to 24000 |
EC50 |
PMID: 20541935 PMID: 21388809 PMID: 24164628 |
| NPC156461 | SLC29A1 | 1 | 17000 | IC50 |
PMID: 23388705 |
| NPC156654 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203719 | HPGD | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203719 | ABAT | 1 | 17100 | IC50 |
PMID: 16290145 |
| NPC203719 | ALDH5A1 | 1 | 15600 | IC50 |
PMID: 16290145 |
| NPC203719 | ALDH1A1 | 2 |
Median: 19622.15 Range: 14125.4 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | PMP22 | 1 | 47754.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GALK1 | 1 | 42128.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK2 | 1 | 40000 | IC50 |
PMID: 17178224 |
| NPC20791 | CD38 | 1 | 37900 | IC50 |
PMID: 21641214 |
| NPC20791 | SORD | 2 |
Median: 106300 Range: 35600 to 177000 |
IC50 |
PMID: 8893834 PMID: 12672241 |
| NPC20791 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | EPHX2 | 1 | 33540 | IC50 |
PMID: 24679441 |
| NPC20791 | DPP4 | 2 |
Median: 81365 Range: 32730 to 130000 |
IC50 |
PMID: 18650094 DOI: 10.1039/C0MD00245C |
| NPC20791 | MAPK1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ADORA3 | 1 | 30000 | Ki |
PMID: 8576921 |
| NPC20791 | PTGS2 | 1 | 28600 | IC50 |
PMID: 17378609 |
| NPC20791 | BLM | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | TDP1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | ALDH1A1 | 6 |
Median: 37646 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CDK6 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 15689157 DOI: 10.1007/s00044-009-9233-5 |
| NPC20791 | PTPN1 | 2 |
Median: 23300 Range: 23300 to 23300 |
IC50 |
PMID: 12419367 PMID: 19297174 |
| NPC20791 | KMT2A | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | AMY1A;AMY1B;AMY1C | 1 | 21400 | IC50 |
PMID: 18507367 |
| NPC20791 | SYK | 1 | 20000 | IC50 |
PMID: 22257213 |
| NPC20791 | HPGD | 2 |
Median: 21169.9 Range: 19952.6 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | APEX1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | CYP2D6 | 1 | 18800 | IC50 |
PMID: 22328583 |
| NPC20791 | USP2 | 2 |
Median: 25057.75 Range: 18492.7 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | GPR35 | 1 | 15400 | IC50 |
PMID: 24900447 |
| NPC20791 | APP | 1 | 15300 | IC50 |
PMID: 26719209 |
| NPC219913 | ALDH5A1 | 1 | 24700 | IC50 |
PMID: 16290145 |
| NPC219913 | ABAT | 1 | 16500 | IC50 |
PMID: 16290145 |
| NPC224651 | EGLN1 | 2 |
Median: 119500 Range: 19000 to 220000 |
IC50 |
PMID: 18942826 PMID: 23234607 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
| NPC254847 | EPHX2 | 1 | 36400 | IC50 |
PMID: 26483136 |
| NPC254847 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | TP53 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | PTP4A3 | 2 |
Median: 31500 Range: 28000 to 35000 |
IC50 |
PMID: 22137788 PMID: 22137788 |
| NPC254847 | NPC1 | 1 | 20596.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | BRCA1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | USP2 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | TDP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | ELANE | 1 | 18000 | IC50 |
PMID: 1578486 |
| NPC282923 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | CA14 | 1 | 42000 | Ki |
PMID: 18579385 |
| NPC65517 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | RECQL | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | CA9 | 1 | 32500 | Ki |
PMID: 18579385 |
| NPC65517 | GMNN | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | PMP22 | 1 | 21331.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | ALOX15 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | MTOR | 2 |
Median: 14689.2 Range: 14689.2 to 14689.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC70744 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC110899 | CA4 | 1 | 10600 | Ki |
PMID: 20185318 |
| NPC12278 | ALOX5 | 1 | 13000 | IC50 |
PMID: 24568174 |
| NPC156461 | MAPK1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC20791 | PIK3CG | 1 | 13790 | IC50 |
PMID: 25050878 |
| NPC20791 | PREP | 1 | 13000 | IC50 |
PMID: 18650094 |
| NPC20791 | LCK | 2 |
Median: 13000 Range: 13000 to 13000 |
IC50 |
PMID: 1995903 PMID: 16441060 |
| NPC20791 | CALM1;CALM2;CALM3 | 1 | 12970 | IC50 |
PMID: 21129983 |
| NPC20791 | PLAU | 1 | 12100 | IC50 |
PMID: 24610996 |
| NPC20791 | CA5B | 1 | 11900 | Ki |
PMID: 20185318 |
| NPC20791 | CYP2C19 | 1 | 10500 | IC50 |
PMID: 22328583 |
| NPC20791 | MMP12 | 1 | 10230 | IC50 |
PMID: 22658537 |
| NPC20791 | HIF1AN | 1 | 10200 | IC50 |
PMID: 19822432 |
| NPC20791 | CYP2C9 | 1 | 10200 | IC50 |
PMID: 22328583 |
| NPC254847 | TDP1 | 2 |
Median: 15186.05 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | CYP2D6 | 2 |
Median: 22106.05 Range: 12589.3 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | THPO | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | ALDH1A1 | 2 |
Median: 13357.35 Range: 12589.3 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | MAPK1 | 2 |
Median: 11904.75 Range: 11220.2 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC254847 | POLB | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC282923 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | HPGD | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC312929 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | CA5A | 1 | 14100 | Ki |
PMID: 18579385 |
| NPC65517 | THPO | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | HBB | 2 |
Median: 26200 Range: 12589.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | CA5B | 1 | 12500 | Ki |
PMID: 18579385 |
| NPC65517 | CA4 | 1 | 10800 | Ki |
PMID: 18579385 |
| NPC65517 | CA1 | 2 |
Median: 10700 Range: 10700 to 10700 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC70744 | CA3 | 1 | 11100 | Ki |
PMID: 20185318 |
| NPC70744 | CA4 | 1 | 10800 | Ki |
PMID: 20185318 |
| NPC70744 | CA5B | 1 | 10500 | Ki |
PMID: 20185318 |
| NPC7814 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |