Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC161571 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | PMP22 | 1 | 42561.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | GAA | 1 | 39506.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | CYP1A1 | 1 | 34000 | IC50 |
PMID: 27265259 |
| NPC161571 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | ALDH1A1 | 4 |
Median: 37646 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | MAOB | 1 | 29370 | IC50 |
DOI: 10.1039/C3MD00376K |
| NPC161571 | BCR | 1 | 28000 | IC50 |
PMID: 16686543 |
| NPC161571 | CYP19A1 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 22115839 PMID: 22386564 |
| NPC161571 | SIRT1 | 3 |
Median: 46200 Range: 23600 to 87200 |
EC50 |
PMID: 18046409 PMID: 23316803 PMID: 23316803 |
| NPC161571 | KDM4E | 4 |
Median: 28370.85 Range: 22387.2 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC161571 | RELA | 1 | 20000 | IC50 |
Patent: Patent: US20130178536 A1 |
| NPC161571 | ODC1 | 1 | 19000 | IC50 |
PMID: 10075742 |
| NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
| NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
| NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC250436 | CREBBP | 1 | 50000 | IC50 |
PMID: 26701186 |
| NPC250436 | EP300 | 1 | 30000 | IC50 |
PMID: 26701186 |
| NPC250436 | MMP7 | 1 | 21500 | IC50 |
PMID: 19524436 |
| NPC250436 | PIN1 | 1 | 20000 | IC50 |
PMID: 23796453 |
| NPC281131 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | MAPT | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | LMNA | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281131 | EPHX2 | 1 | 21760 | IC50 |
PMID: 24679441 |
| NPC303422 | MAPT | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC303422 | GAA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC303422 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC303422 | MAPK1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC303422 | POLB | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | L3MBTL1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | PMP22 | 1 | 30131.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | ALDH1A1 | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | BLM | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | MTOR | 2 |
Median: 23280.9 Range: 23280.9 to 23280.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | KDM4E | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC34864 | SMN1;SMN2 | 3 |
Median: 25118.9 Range: 15848.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC73855 | MPI | 1 | 30965 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC73855 | RECQL | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC73855 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC73855 | MAPT | 2 |
Median: 16815.85 Range: 15848.9 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
| NPC250436 | ELANE | 1 | 12800 | IC50 |
PMID: 20004577 |
| NPC34864 | MYLK | 2 |
Median: 12000 Range: 12000 to 12000 |
IC50 |
PMID: 16441060 PMID: 18077363 |