Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC103342 | KDM4E | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC103342 | CYP3A4 | 1 | 36200 | IC50 |
PMID: 15270556 |
| NPC106976 | PTPN1 | 1 | 19400 | IC50 |
PMID: 17489632 |
| NPC107572 | PDE5A | 1 | 16230 | IC50 |
PMID: 18778098 |
| NPC112701 | GAA | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC112701 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC115159 | TP53 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC115159 | ALOX15 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC115159 | CYP2C9 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC115159 | PKM | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC115159 | CYP2D6 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC133671 | P4HB | 1 | 19020 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC135325 | PTPN1 | 1 | 25500 | IC50 |
PMID: 20724155 |
| NPC13768 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13768 | CYP2D6 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13768 | MAPT | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | GAA | 2 |
Median: 35481.3 Range: 35481.3 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | ALDH1A1 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | HPGD | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | KDM4E | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | MAPT | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | CYP1A2 | 1 | 15848.93 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | GLA | 2 |
Median: 15954.1 Range: 14125.4 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC139891 | TDP1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC142415 | ACP1 | 4 |
Median: 22050 Range: 21200 to 22900 |
IC50 |
PMID: 21453996 PMID: 21453996 PMID: 25264584 PMID: 25264584 |
| NPC142415 | PTPN6 | 2 |
Median: 22760 Range: 14190 to 31330 |
IC50 |
PMID: 18707891 PMID: 27123900 |
| NPC150408 | PTPN1 | 1 | 37500 | IC50 |
PMID: 24047800 |
| NPC158222 | CHRNA7 | 1 | 38000 | EC50 |
PMID: 25232969 |
| NPC166036 | PTPN1 | 1 | 27900 | IC50 |
PMID: 20724155 |
| NPC170475 | P4HB | 1 | 15580 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC172262 | QPCT | 1 | 45200 | IC50 |
PMID: 27061673 |
| NPC172262 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | EPHX2 | 1 | 28430 | IC50 |
PMID: 24679441 |
| NPC179950 | XDH | 1 | 26310 | IC50 |
PMID: 12444671 |
| NPC179950 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC181465 | XDH | 1 | 14800 | IC50 |
PMID: 9461655 |
| NPC183950 | POLB | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC183950 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC183950 | MAPT | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC183950 | KMT2A | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | BACE1 | 1 | 33000 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC19174 | NPSR1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | KMT2A | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | MTOR | 1 | 26121.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | APP | 1 | 19700 | IC50 |
PMID: 23786711 |
| NPC19174 | GMNN | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | PMP22 | 1 | 15101.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC202666 | SLCO1B1 | 1 | 15900 | Ki |
PMID: 12963436 |
| NPC204985 | MAPK1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | HSD17B10 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | KDM4E | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | HPGD | 2 |
Median: 30300.1 Range: 25118.9 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | HPGD | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | CASP7 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | CASP1 | 3 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | TP53 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | RECQL | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | CYP2C9 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | CYP3A4 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC221777 | PTPN1 | 1 | 32600 | IC50 |
PMID: 24047800 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC233455 | PTPN1 | 1 | 45800 | IC50 |
PMID: 21193311 |
| NPC233455 | MAPT | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC233455 | CES1 | 1 | 20970 | IC50 |
PMID: 26900660 |
| NPC233455 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC235239 | PTPN1 | 1 | 44300 | IC50 |
PMID: 24047800 |
| NPC23870 | PTPN1 | 2 |
Median: 19100 Range: 19100 to 19100 |
IC50 |
PMID: 19632832 PMID: 21555221 |
| NPC24394 | PTPN1 | 1 | 20700 | IC50 |
PMID: 21555221 |
| NPC247779 | CTSL | 1 | 30340 | IC50 |
PMID: 23608763 |
| NPC259767 | DPP4 | 1 | 26920 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC272426 | RECQL | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC272426 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC272426 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC272426 | GLA | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC273758 | HPGD | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC273758 | KDM4E | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC273758 | CES1 | 1 | 26000 | Ki |
PMID: 15828829 |
| NPC273758 | TDP1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC27643 | PTPN1 | 2 |
Median: 43950 Range: 30900 to 57000 |
IC50 |
PMID: 19632832 PMID: 24047800 |
| NPC32441 | GSK3B | 1 | 45700 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC32441 | AKR1B1 | 1 | 28870 | IC50 |
PMID: 22261024 |
| NPC32441 | CYP1A2 | 1 | 26339 | IC50 |
PMID: 20696580 |
| NPC32441 | CALM1;CALM2;CALM3 | 1 | 22010 | IC50 |
PMID: 21129983 |
| NPC32441 | CBR1 | 1 | 21480 | IC50 |
PMID: 19097799 |
| NPC32441 | HSD17B10 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC32441 | CYP1A1 | 1 | 15167 | IC50 |
PMID: 20696580 |
| NPC32441 | HSD17B2 | 1 | 14400 | IC50 |
PMID: 18533708 |
| NPC326592 | GAA | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC326592 | POLB | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC37496 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | SYK | 1 | 39000 | IC50 |
PMID: 19254842 |
| NPC39426 | ALDH1A1 | 2 |
Median: 37646 Range: 35481.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | NR1H3 | 1 | 31000 | IC50 |
PMID: 18343126 |
| NPC39426 | DNMT1 | 1 | 30000 | IC50 |
PMID: 25406944 |
| NPC39426 | ODC1 | 1 | 26000 | IC50 |
PMID: 10075742 |
| NPC39426 | PKM | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | SMN1;SMN2 | 3 |
Median: 25118.9 Range: 22387.2 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | NR1H2 | 1 | 22000 | IC50 |
PMID: 18343126 |
| NPC39426 | AKR1B1 | 1 | 20000 | IC50 |
PMID: 22261024 |
| NPC39426 | ALOX15 | 2 |
Median: 25787.7 Range: 19952.6 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | ADORA1 | 1 | 19904 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC39426 | ADORA2A | 1 | 17442 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC39426 | PMP22 | 1 | 16944.1 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | SLC6A3 | 1 | 16918 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC39426 | HSD17B2 | 1 | 16500 | IC50 |
PMID: 18533708 |
| NPC39426 | LMNA | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | HTR2C | 1 | 14910 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC65120 | PTPN1 | 1 | 15600 | IC50 |
PMID: 16580200 |
| NPC6848 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | ALOX15 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC79943 | ALOX12 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC80710 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC80710 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC80710 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC93962 | ACHE | 1 | 15500 | IC50 |
PMID: 26841168 |
| NPC99886 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC99886 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC103342 | RECQL | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC115159 | CYP2C19 | 1 | 12589.25 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC13768 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC13768 | CYP2C9 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | HSD17B10 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | LMNA | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC137949 | SMN1;SMN2 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC142415 | PTPRF | 2 |
Median: 17055 Range: 11800 to 22310 |
IC50 |
PMID: 21453996 PMID: 27123900 |
| NPC142415 | PTPN11 | 1 | 11620 | IC50 |
PMID: 27123900 |
| NPC179950 | ALPL | 1 | 14000 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC187145 | NPSR1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | CHRNA7 | 1 | 11600 | EC50 |
PMID: 25232969 |
| NPC202666 | SLCO1B3 | 1 | 12500 | Ki |
PMID: 12963436 |
| NPC204985 | MAPT | 2 |
Median: 14987.15 Range: 14125.4 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | SMN1;SMN2 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | CYP2C19 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC212794 | MAPT | 2 |
Median: 12672.8 Range: 11220.2 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC259134 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC272426 | HPGD | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC273758 | SMN1;SMN2 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC273758 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC29883 | CA2 | 2 |
Median: 10600 Range: 10600 to 10600 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC307426 | CES1 | 1 | 10530 | IC50 |
PMID: 26900660 |
| NPC32441 | ESR2 | 1 | 13473 | IC50 |
PMID: 17149865 |
| NPC32441 | CYP2C9 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC37496 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | HPGD | 4 |
Median: 19952.6 Range: 11220.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | HTR2A | 1 | 10469 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC4036 | PTPN1 | 1 | 13800 | IC50 |
PMID: 16580200 |
| NPC71853 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC71853 | ALOX12 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |