Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC119949 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC119949 SMN1;SMN2 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC138113 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC139891 TDP1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13991 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC157944 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC157944 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC157944 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC157944 TDP1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC163984 ALDH1A1 2 Median: 25285.5
Range: 22387.2 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC17810 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC17810 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC18205 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC235059 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 GAA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 AKR1B1 1 22900 IC50 PMID: 20805028
NPC247553 CASP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 CASP7 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC252067 TYR 1 50000 IC50 PMID: 14741268
NPC255042 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC257124 AR 2 Median: 19027.305
Range: 19000 to 19054.61
IC50 PMID: 20226658
PMID: 20226658
NPC273033 ALDH1A1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC287331 RECQL 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC287331 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC287331 TSHR 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC292792 PPARA 1 46500 EC50 PMID: 22381047
NPC292792 PPARG 1 40000 EC50 PMID: 22381047
NPC292792 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC434 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC434 HSD17B10 2 Median: 35716.75
Range: 31622.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC434 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC47946 ALDH1A1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC47946 ALOX15 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC68889 ALOX15 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC7491 CYP2C9 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC98028 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC98028 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC98028 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 PTGS1 1 11000 IC50 PMID: 16038536
NPC434 HPGD 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51758 ALOX15 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC7491 CYP2C19 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862