Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC130230 | UGT1A1 | 1 | 41300 | Ki |
PMID: 22822035 |
| NPC131624 | PTGS2 | 3 |
Median: 46000 Range: 46000 to 46000 |
IC50 |
PMID: 16038536 PMID: 24631898 PMID: 25956953 |
| NPC156654 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC173637 | PIM2 | 1 | 25000 | IC50 |
PMID: 18163587 |
| NPC173637 | L3MBTL1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC173637 | XDH | 1 | 14740 | IC50 |
PMID: 12444671 |
| NPC213216 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC213216 | CYP2D6 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC213216 | MAPT | 2 |
Median: 16815.85 Range: 15848.9 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC219913 | ALDH5A1 | 1 | 24700 | IC50 |
PMID: 16290145 |
| NPC219913 | ABAT | 1 | 16500 | IC50 |
PMID: 16290145 |
| NPC223468 | TRPA1 | 1 | 28400 | EC50 |
PMID: 20356305 |
| NPC237435 | CDK1 | 1 | 14360 | IC50 |
PMID: 18639462 |
| NPC239312 | THRB | 2 |
Median: 44668.4 Range: 44668.4 to 44668.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | ABCB1 | 1 | 41000 | IC50 |
PMID: 15481991 |
| NPC239312 | PREP | 1 | 36000 | IC50 |
PMID: 18650094 |
| NPC239312 | SI | 2 |
Median: 43500 Range: 35000 to 52000 |
IC50 |
PMID: 9834167 PMID: 18255289 |
| NPC239312 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | HBB | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | GPR35 | 1 | 28200 | IC50 |
PMID: 24900447 |
| NPC239312 | L3MBTL1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC241498 | ATM | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC241498 | TDP1 | 2 |
Median: 46590.9 Range: 22387.2 to 70794.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC241498 | MAPT | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC246679 | NFKB1 | 1 | 50000 | IC50 |
PMID: 20980154 |
| NPC255042 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC257124 | AR | 2 |
Median: 19027.305 Range: 19000 to 19054.61 |
IC50 |
PMID: 20226658 PMID: 20226658 |
| NPC26960 | PTPN1 | 1 | 32600 | IC50 |
PMID: 25497963 |
| NPC279121 | GALK1 | 1 | 47269 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | TSHR | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | CYP2C9 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | GAA | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | DAPK1 | 1 | 21000 | IC50 |
PMID: 26322379 |
| NPC279121 | CDK2 | 1 | 20000 | IC50 |
PMID: 17178224 |
| NPC279121 | TDP1 | 2 |
Median: 29881.65 Range: 19952.6 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | ABCB1 | 1 | 19600 | IC50 |
PMID: 15240100 |
| NPC279121 | GPR35 | 1 | 18600 | IC50 |
PMID: 24900447 |
| NPC279121 | AMY1A;AMY1B;AMY1C | 1 | 18400 | IC50 |
PMID: 18507367 |
| NPC279121 | MMP3 | 1 | 16200 | IC50 |
PMID: 22658537 |
| NPC279121 | CYP2C19 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | BLM | 2 |
Median: 17900.75 Range: 15848.9 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC292792 | PPARA | 1 | 46500 | EC50 |
PMID: 22381047 |
| NPC292792 | PPARG | 1 | 40000 | EC50 |
PMID: 22381047 |
| NPC292792 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC301585 | PPARD | 1 | 24000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC301585 | PPARG | 1 | 21000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC32441 | GSK3B | 1 | 45700 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC32441 | AKR1B1 | 1 | 28870 | IC50 |
PMID: 22261024 |
| NPC32441 | CYP1A2 | 1 | 26339 | IC50 |
PMID: 20696580 |
| NPC32441 | CALM1;CALM2;CALM3 | 1 | 22010 | IC50 |
PMID: 21129983 |
| NPC32441 | CBR1 | 1 | 21480 | IC50 |
PMID: 19097799 |
| NPC32441 | HSD17B10 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC32441 | CYP1A1 | 1 | 15167 | IC50 |
PMID: 20696580 |
| NPC32441 | HSD17B2 | 1 | 14400 | IC50 |
PMID: 18533708 |
| NPC43211 | SLCO2B1 | 1 | 25900 | Ki |
PMID: 22822035 |
| NPC44328 | TDP1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | APEX1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | THRB | 2 |
Median: 44964.7 Range: 39810.7 to 50118.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | BACE1 | 2 |
Median: 38500 Range: 38500 to 38500 |
IC50 |
PMID: 22243648 DOI: 10.1007/s00044-012-0353-y |
| NPC50898 | BCHE | 1 | 37400 | Ki |
PMID: 19879672 |
| NPC50898 | HBB | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | DAPK1 | 1 | 31000 | IC50 |
PMID: 26322379 |
| NPC50898 | NPSR1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | HPGD | 3 |
Median: 28183.8 Range: 22387.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | NFKB1 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | MAPK1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | CA14 | 1 | 42000 | Ki |
PMID: 18579385 |
| NPC65517 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | RECQL | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | CA9 | 1 | 32500 | Ki |
PMID: 18579385 |
| NPC65517 | GMNN | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | PMP22 | 1 | 21331.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | ALOX15 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | MTOR | 2 |
Median: 14689.2 Range: 14689.2 to 14689.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC68889 | ALOX15 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC7491 | CYP2C9 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC79056 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC79056 | CTDSP1 | 1 | 20733 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC79672 | PTGS1 | 1 | 22200 | IC50 |
PMID: 25442305 |
| NPC79943 | ALOX12 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
| NPC99886 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC99886 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC148216 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC213216 | TP53 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC237435 | PREP | 2 |
Median: 12150 Range: 12000 to 12300 |
IC50 |
PMID: 18650094 PMID: 20058865 |
| NPC239312 | CREB1 | 1 | 13500 | AC50 |
PMID: 18722769 |
| NPC239312 | SMN1;SMN2 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | ALDH1A1 | 2 |
Median: 13104.55 Range: 11220.2 to 14988.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC239312 | GLO1 | 1 | 11000 | IC50 |
PMID: 18258440 |
| NPC239312 | PTPRS | 1 | 10300 | IC50 |
PMID: 26602279 |
| NPC257124 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC257124 | PTGS1 | 1 | 11000 | IC50 |
PMID: 16038536 |
| NPC259134 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | MAPT | 3 |
Median: 12589.3 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | SYK | 1 | 12000 | IC50 |
PMID: 22257213 |
| NPC279121 | HPGD | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC279121 | MMP13 | 1 | 10050 | IC50 |
PMID: 22658537 |
| NPC32441 | ESR2 | 1 | 13473 | IC50 |
PMID: 17149865 |
| NPC32441 | CYP2C9 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | SMN1;SMN2 | 5 |
Median: 22387.2 Range: 14125.4 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | MAOB | 1 | 12800 | IC50 |
PMID: 20045650 |
| NPC50898 | CYP2D6 | 2 |
Median: 26200 Range: 12589.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | LMNA | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | AKR1B1 | 1 | 11900 | IC50 |
PMID: 26529431 |
| NPC50898 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | CA5A | 1 | 14100 | Ki |
PMID: 18579385 |
| NPC65517 | THPO | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | HBB | 2 |
Median: 26200 Range: 12589.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC65517 | CA5B | 1 | 12500 | Ki |
PMID: 18579385 |
| NPC65517 | CA4 | 1 | 10800 | Ki |
PMID: 18579385 |
| NPC65517 | CA1 | 2 |
Median: 10700 Range: 10700 to 10700 |
Ki |
PMID: 18501600 PMID: 18579385 |
| NPC7491 | CYP2C19 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |