Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC103213 UGT1A1 2 Median: 43500
Range: 40000 to 47000
IC50 PMID: 21030469
PMID: 21030469
NPC103213 ALOX15 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103213 MAPT 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13991 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203719 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203719 ABAT 1 17100 IC50 PMID: 16290145
NPC203719 ALDH5A1 1 15600 IC50 PMID: 16290145
NPC203719 ALDH1A1 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC207554 KMT2A 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC207554 MAPT 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 AR 2 Median: 19027.305
Range: 19000 to 19054.61
IC50 PMID: 20226658
PMID: 20226658
NPC269919 HSD17B10 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC269919 ALDH1A1 1 14321.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC269919 HPGD 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC57279 TSHR 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC61473 PTPN2 1 35090 IC50 PMID: 25497963
NPC61473 CDC25B 1 23230 IC50 PMID: 25497963
NPC96102 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC96102 CYP2D6 1 31622.78 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC96102 CYP2A13 1 16000 Ki PMID: 22696418
NPC96102 CTSK 1 15000 IC50 PMID: 11975521
NPC103213 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC141953 TSHR 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC153556 RGS12 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC207554 HTT 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 ALDH1A1 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257124 PTGS1 1 11000 IC50 PMID: 16038536
NPC269919 KDM4E 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC96102 NFKB1 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862