Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC116775 BCHE 1 43100 Ki PMID: 19879672
NPC116775 ALDH1A1 2 Median: 35716.75
Range: 31622.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC116775 CDK6 2 Median: 22000
Range: 22000 to 22000
IC50 PMID: 15689157
DOI: 10.1007/s00044-009-9233-5
NPC116775 GLO1 1 20600 IC50 PMID: 18258440
NPC116775 KDM4E 2 Median: 27829.8
Range: 15848.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 HSD17B10 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 BACE1 1 14700 IC50 DOI: 10.1007/s00044-012-0353-y
NPC179950 EPHX2 1 28430 IC50 PMID: 24679441
NPC179950 XDH 1 26310 IC50 PMID: 12444671
NPC179950 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC296030 ALOX5 1 41400 IC50 PMID: 21800856
NPC39929 PTGES 1 42000 IC50 PMID: 21800856
NPC39929 ALOX5 1 27200 IC50 PMID: 21800856
NPC62735 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC62735 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC62735 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC62735 HPGD 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC62735 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC62735 MAPT 2 Median: 15954.1
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC116775 MAPT 2 Median: 14219.1
Range: 12589.3 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC179950 ALPL 1 14000 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC179950 KDM4E 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC300267 PTGES 1 13000 IC50 PMID: 21800856
NPC51641 PTGES 1 13500 IC50 PMID: 21800856
NPC62735 PTGES 1 11000 IC50 PMID: 21800856