Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC138113 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC13991 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC148523 | PREP | 1 | 36320 | IC50 |
PMID: 15730241 |
| NPC149184 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC149184 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC163556 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC163556 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC231772 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | TP53 | 2 |
Median: 28370.85 Range: 25118.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | RECQL | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC287331 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC307176 | ABCB1 | 6 |
Median: 68538.94 Range: 47863.01 to 192200 |
IC50 |
PMID: 11716514 PMID: 11716514 PMID: 11716514 PMID: 17890094 PMID: 17890094 PMID: 18678495 |
| NPC307176 | MAPT | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC307176 | KDM4E | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC307176 | SLC22A2 | 1 | 26700 | IC50 |
PMID: 12110607 |
| NPC307176 | ALDH1A1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC307176 | FABP2 | 1 | 20000 | Ki |
PMID: 18533710 |
| NPC307176 | ABCB11 | 2 |
Median: 120950 Range: 17300 to 224600 |
IC50 |
PMID: 12739759 PMID: 12739759 |
| NPC307176 | SOAT1 | 1 | 17000 | IC50 |
PMID: 3100794 |
| NPC47946 | ALDH1A1 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC47946 | ALOX15 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | APEX1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | THRB | 2 |
Median: 44964.7 Range: 39810.7 to 50118.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | BACE1 | 2 |
Median: 38500 Range: 38500 to 38500 |
IC50 |
PMID: 22243648 DOI: 10.1007/s00044-012-0353-y |
| NPC50898 | BCHE | 1 | 37400 | Ki |
PMID: 19879672 |
| NPC50898 | HBB | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | DAPK1 | 1 | 31000 | IC50 |
PMID: 26322379 |
| NPC50898 | NPSR1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | HPGD | 3 |
Median: 28183.8 Range: 22387.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | NFKB1 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | MAPK1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC68889 | ALOX15 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC71074 | PTPN6 | 1 | 24560 | IC50 |
PMID: 18707891 |
| NPC71074 | PYGM | 1 | 20000 | IC50 |
PMID: 16169219 |
| NPC95868 | MAPT | 2 |
Median: 37646 Range: 35481.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC95868 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC192638 | TOP2A | 1 | 10400 | IC50 |
PMID: 11754608 |
| NPC231772 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | SMN1;SMN2 | 2 |
Median: 19622.15 Range: 14125.4 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | USP2 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC231772 | CYP2D6 | 1 | 12589.25 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC307176 | SMN1;SMN2 | 2 |
Median: 14987.15 Range: 14125.4 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC307176 | MAPK1 | 2 |
Median: 26968.05 Range: 14125.4 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC307176 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | SMN1;SMN2 | 5 |
Median: 22387.2 Range: 14125.4 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | MAOB | 1 | 12800 | IC50 |
PMID: 20045650 |
| NPC50898 | CYP2D6 | 2 |
Median: 26200 Range: 12589.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | LMNA | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC50898 | AKR1B1 | 1 | 11900 | IC50 |
PMID: 26529431 |
| NPC50898 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC51758 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC71074 | POLB | 1 | 12600 | IC50 |
PMID: 15165161 |
| NPC71074 | HTT | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC71074 | PTPN2 | 1 | 11310 | IC50 |
PMID: 18707891 |
| NPC95868 | HTT | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |