Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC203719 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203719 ABAT 1 17100 IC50 PMID: 16290145
NPC203719 ALDH5A1 1 15600 IC50 PMID: 16290145
NPC203719 ALDH1A1 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC212794 HPGD 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC212794 CASP7 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC212794 CASP1 3 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC212794 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC212794 HSD17B10 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC212794 TP53 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC212794 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC212794 RECQL 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC212794 CYP2C9 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC212794 CYP3A4 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC260491 MAPT 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC260491 RECQL 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 ALDH1A1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 TERT 1 37000 IC50 PMID: 22336246
NPC61473 PTPN2 1 35090 IC50 PMID: 25497963
NPC61473 CDC25B 1 23230 IC50 PMID: 25497963
NPC210148 CYP3A4 1 13400 IC50 PMID: 16562853
NPC212794 CYP2C19 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC212794 MAPT 2 Median: 12672.8
Range: 11220.2 to 14125.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC260491 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC53069 TSHR 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 MAPT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862