Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC142415 ACP1 4 Median: 22050
Range: 21200 to 22900
IC50 PMID: 21453996
PMID: 21453996
PMID: 25264584
PMID: 25264584
NPC142415 PTPN6 2 Median: 22760
Range: 14190 to 31330
IC50 PMID: 18707891
PMID: 27123900
NPC186098 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC186098 HPGD 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC264317 POLB 2 Median: 44925
Range: 43600 to 46250
IC50 PMID: 14640519
PMID: 18343122
NPC264317 GLI1 2 Median: 32000
Range: 32000 to 32000
IC50 PMID: 18842418
PMID: 19309080
NPC266689 LMNA 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC318107 CA2 2 Median: 30000
Range: 30000 to 30000
Ki PMID: 15664815
PMID: 19297172
NPC142415 PTPRF 2 Median: 17055
Range: 11800 to 22310
IC50 PMID: 21453996
PMID: 27123900
NPC142415 PTPN11 1 11620 IC50 PMID: 27123900
NPC264317 AKR1B1 1 11000 IC50 PMID: 21561086