Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC119133 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC126029 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC126681 | SLC6A9 | 1 | 31600 | IC50 |
PMID: 24461352 |
| NPC156654 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC156654 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | TSHR | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | MAPT | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219143 | CYP1A2 | 1 | 39810.72 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219143 | KDM4E | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | PTGS1 | 2 |
Median: 58350 Range: 36700 to 80000 |
IC50 |
PMID: 11858749 PMID: 16038536 |
| NPC219876 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | NPSR1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | BLM | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | RECQL | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | MAPT | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | APEX1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC256849 | ADORA1 | 5 |
Median: 44900 Range: 44000 to 44900 |
Ki |
PMID: 21664729 PMID: 23602401 PMID: 24139167 PMID: 24139167 PMID: 24164628 |
| NPC256849 | ADORA2A | 1 | 20472 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC279406 | MMP2 | 1 | 31400 | IC50 |
PMID: 20053563 |
| NPC33338 | CYP2C9 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC46335 | MMP2 | 1 | 43200 | IC50 |
PMID: 20053563 |
| NPC46335 | MMP9 | 1 | 39200 | IC50 |
PMID: 20053563 |
| NPC51146 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC51146 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC51146 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC51146 | MAOA | 1 | 21300 | IC50 |
PMID: 23517722 |
| NPC126029 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC126029 | KDM4E | 2 |
Median: 16803.7 Range: 11220.2 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC203468 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | KDM4E | 2 |
Median: 19622.15 Range: 14125.4 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC219876 | POLB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC256849 | ADORA3 | 3 |
Median: 13300 Range: 13300 to 13300 |
Ki |
PMID: 12139454 PMID: 24139167 PMID: 24139167 |
| NPC256849 | ADORA2B | 10 |
Median: 27150 Range: 10400 to 33800 |
Ki |
PMID: 12014951 PMID: 19569717 PMID: 19569717 PMID: 20188574 PMID: 20537438 PMID: 21664729 PMID: 24139167 PMID: 24139167 PMID: 24164628 PMID: 26824742 |
| NPC256849 | GDA | 1 | 10200 | Ki |
PMID: 20716488 |
| NPC277510 | HDAC11 | 1 | 12900 | IC50 |
PMID: 24328302 |
| NPC33338 | TSHR | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC33338 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |