Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC19174 | BACE1 | 1 | 33000 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC19174 | NPSR1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | KMT2A | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | MTOR | 1 | 26121.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | APP | 1 | 19700 | IC50 |
PMID: 23786711 |
| NPC19174 | GMNN | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | PMP22 | 1 | 15101.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC200060 | KDM4E | 1 | 35481.3 | Potency |
PMID: 15165131 |
| NPC200060 | HPGD | 1 | 31622.8 | Potency |
PMID: 17665951 |
| NPC200060 | ALDH1A1 | 1 | 31622.8 | Potency |
PMID: 17125224 |
| NPC200060 | HSD17B10 | 1 | 31622.8 | Potency |
DOI: 10.1016/S0960-894X(01)80948-3 |
| NPC209560 | HSD17B10 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | KDM4E | 2 |
Median: 29903.3 Range: 28183.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | HPGD | 2 |
Median: 30300.1 Range: 25118.9 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC209560 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | AKR1B10 | 1 | 36100 | IC50 |
PMID: 26529431 |
| NPC294409 | HPGD | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | KDM4E | 2 |
Median: 33552.05 Range: 31622.8 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | HSD17B10 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | LMNA | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | CYP3A4 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | SMN1;SMN2 | 2 |
Median: 18867.7 Range: 17782.8 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | MAPK1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | ALOX12 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC32441 | GSK3B | 1 | 45700 | IC50 |
DOI: 10.1007/s00044-012-0353-y |
| NPC32441 | AKR1B1 | 1 | 28870 | IC50 |
PMID: 22261024 |
| NPC32441 | CYP1A2 | 1 | 26339 | IC50 |
PMID: 20696580 |
| NPC32441 | CALM1;CALM2;CALM3 | 1 | 22010 | IC50 |
PMID: 21129983 |
| NPC32441 | CBR1 | 1 | 21480 | IC50 |
PMID: 19097799 |
| NPC32441 | HSD17B10 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC32441 | CYP1A1 | 1 | 15167 | IC50 |
PMID: 20696580 |
| NPC32441 | HSD17B2 | 1 | 14400 | IC50 |
PMID: 18533708 |
| NPC39426 | SYK | 1 | 39000 | IC50 |
PMID: 19254842 |
| NPC39426 | ALDH1A1 | 2 |
Median: 37646 Range: 35481.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | NR1H3 | 1 | 31000 | IC50 |
PMID: 18343126 |
| NPC39426 | DNMT1 | 1 | 30000 | IC50 |
PMID: 25406944 |
| NPC39426 | ODC1 | 1 | 26000 | IC50 |
PMID: 10075742 |
| NPC39426 | PKM | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | SMN1;SMN2 | 3 |
Median: 25118.9 Range: 22387.2 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | NR1H2 | 1 | 22000 | IC50 |
PMID: 18343126 |
| NPC39426 | AKR1B1 | 1 | 20000 | IC50 |
PMID: 22261024 |
| NPC39426 | ALOX15 | 2 |
Median: 25787.7 Range: 19952.6 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | ADORA1 | 1 | 19904 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC39426 | ADORA2A | 1 | 17442 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC39426 | PMP22 | 1 | 16944.1 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | SLC6A3 | 1 | 16918 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC39426 | HSD17B2 | 1 | 16500 | IC50 |
PMID: 18533708 |
| NPC39426 | LMNA | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | HTR2C | 1 | 14910 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC55162 | CYP3A4 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PMID: 8277312 PMID: 19506060 |
| NPC55162 | ALDH1A1 | 1 | 39810.7 | Potency |
PMID: 26290401 |
| NPC55162 | HPGD | 1 | 31622.8 | Potency |
PMID: 24211632 |
| NPC55162 | KDM4E | 1 | 28183.8 | Potency |
PMID: 20547812 |
| NPC55162 | HSD17B10 | 1 | 25118.9 | Potency |
PMID: 18411316 |
| NPC80710 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC80710 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC80710 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC19174 | CHRNA7 | 1 | 11600 | EC50 |
PMID: 25232969 |
| NPC209560 | SMN1;SMN2 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | CBR1 | 1 | 12710 | IC50 |
PMID: 19097799 |
| NPC32441 | ESR2 | 1 | 13473 | IC50 |
PMID: 17149865 |
| NPC32441 | CYP2C9 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | HPGD | 4 |
Median: 19952.6 Range: 11220.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | HTR2A | 1 | 10469 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |