Plant ingredients against the target with activities between 10uM and 50uM
Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
---|---|---|---|---|---|
NPC156654 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC156654 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC156654 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC161571 | POLB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC161571 | PMP22 | 1 | 42561.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC161571 | GAA | 1 | 39506.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC161571 | CYP1A1 | 1 | 34000 | IC50 |
PMID: 27265259 |
NPC161571 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC161571 | ALDH1A1 | 4 |
Median: 37646 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC161571 | MAOB | 1 | 29370 | IC50 |
DOI: 10.1039/C3MD00376K |
NPC161571 | BCR | 1 | 28000 | IC50 |
PMID: 16686543 |
NPC161571 | CYP19A1 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 22115839 PMID: 22386564 |
NPC161571 | SIRT1 | 3 |
Median: 46200 Range: 23600 to 87200 |
EC50 |
PMID: 18046409 PMID: 23316803 PMID: 23316803 |
NPC161571 | KDM4E | 4 |
Median: 28370.85 Range: 22387.2 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC161571 | RELA | 1 | 20000 | IC50 |
Patent: Patent: US20130178536 A1 |
NPC161571 | ODC1 | 1 | 19000 | IC50 |
PMID: 10075742 |
NPC173637 | PIM2 | 1 | 25000 | IC50 |
PMID: 18163587 |
NPC173637 | L3MBTL1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC173637 | XDH | 1 | 14740 | IC50 |
PMID: 12444671 |
NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC179950 | EPHX2 | 1 | 28430 | IC50 |
PMID: 24679441 |
NPC179950 | XDH | 1 | 26310 | IC50 |
PMID: 12444671 |
NPC179950 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC203468 | TSHR | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC203468 | MAPT | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC203468 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC203468 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | PMP22 | 1 | 47754.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | GALK1 | 1 | 42128.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | CDK2 | 1 | 40000 | IC50 |
PMID: 17178224 |
NPC20791 | CD38 | 1 | 37900 | IC50 |
PMID: 21641214 |
NPC20791 | SORD | 2 |
Median: 106300 Range: 35600 to 177000 |
IC50 |
PMID: 8893834 PMID: 12672241 |
NPC20791 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | EPHX2 | 1 | 33540 | IC50 |
PMID: 24679441 |
NPC20791 | DPP4 | 2 |
Median: 81365 Range: 32730 to 130000 |
IC50 |
PMID: 18650094 DOI: 10.1039/C0MD00245C |
NPC20791 | MAPK1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | ADORA3 | 1 | 30000 | Ki |
PMID: 8576921 |
NPC20791 | PTGS2 | 1 | 28600 | IC50 |
PMID: 17378609 |
NPC20791 | BLM | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | TDP1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | ALDH1A1 | 6 |
Median: 37646 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | CDK6 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 15689157 DOI: 10.1007/s00044-009-9233-5 |
NPC20791 | PTPN1 | 2 |
Median: 23300 Range: 23300 to 23300 |
IC50 |
PMID: 12419367 PMID: 19297174 |
NPC20791 | KMT2A | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | AMY1A;AMY1B;AMY1C | 1 | 21400 | IC50 |
PMID: 18507367 |
NPC20791 | SYK | 1 | 20000 | IC50 |
PMID: 22257213 |
NPC20791 | HPGD | 2 |
Median: 21169.9 Range: 19952.6 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | APEX1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | CYP2D6 | 1 | 18800 | IC50 |
PMID: 22328583 |
NPC20791 | USP2 | 2 |
Median: 25057.75 Range: 18492.7 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | GPR35 | 1 | 15400 | IC50 |
PMID: 24900447 |
NPC20791 | APP | 1 | 15300 | IC50 |
PMID: 26719209 |
NPC219876 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC219876 | PTGS1 | 2 |
Median: 58350 Range: 36700 to 80000 |
IC50 |
PMID: 11858749 PMID: 16038536 |
NPC219876 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC219876 | NPSR1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC219876 | BLM | 2 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC219876 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC219876 | RECQL | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC219876 | MAPT | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC219876 | APEX1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC248573 | ALOX15 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC248573 | HPGD | 2 |
Median: 25665.1 Range: 15848.9 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC248573 | SMN1;SMN2 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | EPHX2 | 1 | 36400 | IC50 |
PMID: 26483136 |
NPC254847 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | TP53 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | PTP4A3 | 2 |
Median: 31500 Range: 28000 to 35000 |
IC50 |
PMID: 22137788 PMID: 22137788 |
NPC254847 | NPC1 | 1 | 20596.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC271385 | ESR1 | 1 | 20000 | IC50 |
PMID: 11459643 |
NPC282923 | BRCA1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC282923 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC282923 | USP2 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC282923 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC282923 | TDP1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC282923 | ELANE | 1 | 18000 | IC50 |
PMID: 1578486 |
NPC282923 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | BLM | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | HPGD | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | PLEC | 2 |
Median: 93960.05 Range: 32104.8 to 155815.3 |
IC50 |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | ALDH1A1 | 2 |
Median: 33997.25 Range: 28183.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | THRB | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | CASP7 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | PTPN7 | 1 | 19620 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | BCHE | 1 | 17000 | IC50 |
PMID: 24568372 |
NPC288089 | CASP1 | 5 |
Median: 25118.9 Range: 15848.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | TSHR | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | ALOX12 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC303422 | MAPT | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC303422 | GAA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC303422 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC303422 | MAPK1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC303422 | POLB | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC312929 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC312929 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC312929 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | APEX1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | THRB | 2 |
Median: 44964.7 Range: 39810.7 to 50118.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | BACE1 | 2 |
Median: 38500 Range: 38500 to 38500 |
IC50 |
PMID: 22243648 DOI: 10.1007/s00044-012-0353-y |
NPC50898 | BCHE | 1 | 37400 | Ki |
PMID: 19879672 |
NPC50898 | HBB | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | HSD17B10 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | DAPK1 | 1 | 31000 | IC50 |
PMID: 26322379 |
NPC50898 | NPSR1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | HPGD | 3 |
Median: 28183.8 Range: 22387.2 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | NFKB1 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | MAPK1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC179950 | ALPL | 1 | 14000 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC179950 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC203468 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | PIK3CG | 1 | 13790 | IC50 |
PMID: 25050878 |
NPC20791 | PREP | 1 | 13000 | IC50 |
PMID: 18650094 |
NPC20791 | LCK | 2 |
Median: 13000 Range: 13000 to 13000 |
IC50 |
PMID: 1995903 PMID: 16441060 |
NPC20791 | CALM1;CALM2;CALM3 | 1 | 12970 | IC50 |
PMID: 21129983 |
NPC20791 | PLAU | 1 | 12100 | IC50 |
PMID: 24610996 |
NPC20791 | CA5B | 1 | 11900 | Ki |
PMID: 20185318 |
NPC20791 | CYP2C19 | 1 | 10500 | IC50 |
PMID: 22328583 |
NPC20791 | MMP12 | 1 | 10230 | IC50 |
PMID: 22658537 |
NPC20791 | HIF1AN | 1 | 10200 | IC50 |
PMID: 19822432 |
NPC20791 | CYP2C9 | 1 | 10200 | IC50 |
PMID: 22328583 |
NPC219876 | KDM4E | 2 |
Median: 19622.15 Range: 14125.4 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC219876 | POLB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
NPC248573 | MAPT | 2 |
Median: 14125.4 Range: 14125.4 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC248573 | THPO | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC248573 | KDM4E | 2 |
Median: 20386.55 Range: 12589.3 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC248573 | HSD17B10 | 4 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | TDP1 | 2 |
Median: 15186.05 Range: 12589.3 to 17782.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | CYP2D6 | 2 |
Median: 22106.05 Range: 12589.3 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | THPO | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | ALDH1A1 | 2 |
Median: 13357.35 Range: 12589.3 to 14125.4 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | MAPK1 | 2 |
Median: 11904.75 Range: 11220.2 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC254847 | POLB | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC282923 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | KDM4E | 2 |
Median: 21154.6 Range: 14125.4 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | HSD17B10 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | HIF1A | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | LMNA | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC288089 | POLB | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC293378 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC312929 | HPGD | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC312929 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | SMN1;SMN2 | 5 |
Median: 22387.2 Range: 14125.4 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | MAOB | 1 | 12800 | IC50 |
PMID: 20045650 |
NPC50898 | CYP2D6 | 2 |
Median: 26200 Range: 12589.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | GMNN | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | LMNA | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC50898 | AKR1B1 | 1 | 11900 | IC50 |
PMID: 26529431 |
NPC50898 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |