Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC115284 TP53 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC115284 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC142415 ACP1 4 Median: 22050
Range: 21200 to 22900
IC50 PMID: 21453996
PMID: 21453996
PMID: 25264584
PMID: 25264584
NPC142415 PTPN6 2 Median: 22760
Range: 14190 to 31330
IC50 PMID: 18707891
PMID: 27123900
NPC261831 BLM 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 CYP19A1 1 32700 IC50 PMID: 16643058
NPC261831 TOP1 1 31000 IC50 PMID: 12444712
NPC261831 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 FABP4 1 26100 IC50 PMID: 20471252
NPC261831 KMT2A 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 ATM 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC261831 HSD17B10 2 Median: 17900.75
Range: 15848.9 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC290005 OPRD1 1 44174 EC50 PubChem BioAssay data set
CHEMBL1201862
NPC290005 RAD52 1 35210 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC290005 MAPT 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC317145 TDP1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 ALDH1A1 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 TERT 1 37000 IC50 PMID: 22336246
NPC142415 PTPRF 2 Median: 17055
Range: 11800 to 22310
IC50 PMID: 21453996
PMID: 27123900
NPC142415 PTPN11 1 11620 IC50 PMID: 27123900
NPC261831 KCNH2 1 10410 EC50 PubChem BioAssay data set
CHEMBL1201862
NPC53069 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC53069 TSHR 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC53069 MAPT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862