Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC125732 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC125732 CYP2C19 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC125732 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC125732 HTR3A 1 26000 EC50 PMID: 18033297
NPC223125 TOP2A 1 25800 IC50 PMID: 22014547
NPC229235 HTR2A 2 Median: 16800
Range: 16800 to 16800
Ki PMID: 11931619
PMID: 18847250
NPC229235 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC61871 PTGS1 1 19750 IC50 PMID: 21345672
NPC61871 PTGS2 1 15350 IC50 PMID: 21345672
NPC125732 L3MBTL1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC166934 ABCG2 1 12300 IC50 PMID: 21275386