Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC113733 | POLB | 2 |
Median: 51840 Range: 43400 to 60280 |
IC50 |
PMID: 14640519 PMID: 18343122 |
| NPC142415 | ACP1 | 4 |
Median: 22050 Range: 21200 to 22900 |
IC50 |
PMID: 21453996 PMID: 21453996 PMID: 25264584 PMID: 25264584 |
| NPC142415 | PTPN6 | 2 |
Median: 22760 Range: 14190 to 31330 |
IC50 |
PMID: 18707891 PMID: 27123900 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC281398 | MGLL | 1 | 48000 | IC50 |
DOI: 10.1039/C4MD00186A |
| NPC281398 | RECQL | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC281398 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281398 | ALOX12 | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281398 | POLB | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281398 | L3MBTL1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC281398 | KDM4E | 3 |
Median: 19952.6 Range: 17782.8 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC281398 | TDP1 | 2 |
Median: 20085 Range: 17782.8 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC281398 | HPGD | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC281398 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC51700 | PPARA | 1 | 41310 | EC50 |
PMID: 21855333 |
| NPC51700 | AKR1B1 | 1 | 41000 | IC50 |
PMID: 21561086 |
| NPC51700 | CYP19A1 | 1 | 32000 | IC50 |
PMID: 18192087 |
| NPC51700 | PTPN6 | 1 | 25780 | IC50 |
PMID: 18707891 |
| NPC51700 | POLB | 1 | 18600 | IC50 |
PMID: 15165161 |
| NPC51700 | CTSD | 1 | 18200 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
| NPC51700 | SLCO1B1 | 1 | 15848.93 | IC50 |
PMID: 23571415 |
| NPC77000 | PTPRC | 1 | 41400 | IC50 |
PMID: 23957426 |
| NPC77000 | RECQL | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77000 | PTPN6 | 1 | 39500 | IC50 |
PMID: 23957426 |
| NPC77000 | PTPRF | 1 | 36900 | IC50 |
PMID: 23957426 |
| NPC77000 | PTPN1 | 1 | 33500 | IC50 |
PMID: 23957426 |
| NPC77000 | KMT2A | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77000 | TDP1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77000 | NPSR1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77000 | PTPN11 | 2 |
Median: 33840 Range: 22500 to 45180 |
IC50 |
PMID: 23957426 PMID: 23957426 |
| NPC77000 | POLB | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77000 | KDM4E | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC77000 | L3MBTL1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC93241 | CES1 | 1 | 26250 | Ki |
PMID: 23286284 |
| NPC93241 | BLM | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC93241 | POLB | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC142415 | PTPRF | 2 |
Median: 17055 Range: 11800 to 22310 |
IC50 |
PMID: 21453996 PMID: 27123900 |
| NPC142415 | PTPN11 | 1 | 11620 | IC50 |
PMID: 27123900 |
| NPC192638 | TOP2A | 1 | 10400 | IC50 |
PMID: 11754608 |
| NPC281398 | TP53 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC51700 | SLCO1B3 | 1 | 11481.54 | IC50 |
PMID: 23571415 |
| NPC77000 | ALDH1A1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC93241 | TDP1 | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |