Plant ingredients against the target with activities between 10uM and 50uM
Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
---|---|---|---|---|---|
NPC10251 | L3MBTL1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC107482 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC1075 | CYP2C9 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC113733 | POLB | 2 |
Median: 51840 Range: 43400 to 60280 |
IC50 |
PMID: 14640519 PMID: 18343122 |
NPC115284 | TP53 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC115284 | SMN1;SMN2 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC119949 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC119949 | SMN1;SMN2 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC126681 | SLC6A9 | 1 | 31600 | IC50 |
PMID: 24461352 |
NPC129976 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC137958 | CYP1A2 | 1 | 39810.72 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC137958 | SLC1A3 | 1 | 35000 | Ki |
PMID: 18578477 |
NPC139416 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC139416 | CYP2A6 | 2 |
Median: 33981.265 Range: 33962.53 to 34000 |
IC50 |
PMID: 15658857 PMID: 19110342 |
NPC139891 | TDP1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC142415 | ACP1 | 4 |
Median: 22050 Range: 21200 to 22900 |
IC50 |
PMID: 21453996 PMID: 21453996 PMID: 25264584 PMID: 25264584 |
NPC142415 | PTPN6 | 2 |
Median: 22760 Range: 14190 to 31330 |
IC50 |
PMID: 18707891 PMID: 27123900 |
NPC144682 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC145038 | MPI | 1 | 21303 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC149436 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC156654 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC156654 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC156654 | POLB | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC179950 | EPHX2 | 1 | 28430 | IC50 |
PMID: 24679441 |
NPC179950 | XDH | 1 | 26310 | IC50 |
PMID: 12444671 |
NPC179950 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC188341 | TP53 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC188341 | CYP2C19 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC192744 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC200845 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC200845 | TDP1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC201844 | PPARA | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC201844 | PPARD | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC201844 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC203719 | HPGD | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC203719 | ABAT | 1 | 17100 | IC50 |
PMID: 16290145 |
NPC203719 | ALDH5A1 | 1 | 15600 | IC50 |
PMID: 16290145 |
NPC203719 | ALDH1A1 | 2 |
Median: 19622.15 Range: 14125.4 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | PMP22 | 1 | 47754.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | THRB | 1 | 44668.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | GALK1 | 1 | 42128.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | CDK2 | 1 | 40000 | IC50 |
PMID: 17178224 |
NPC20791 | CD38 | 1 | 37900 | IC50 |
PMID: 21641214 |
NPC20791 | SORD | 2 |
Median: 106300 Range: 35600 to 177000 |
IC50 |
PMID: 8893834 PMID: 12672241 |
NPC20791 | SMN1;SMN2 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | EPHX2 | 1 | 33540 | IC50 |
PMID: 24679441 |
NPC20791 | DPP4 | 2 |
Median: 81365 Range: 32730 to 130000 |
IC50 |
PMID: 18650094 DOI: 10.1039/C0MD00245C |
NPC20791 | MAPK1 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | ADORA3 | 1 | 30000 | Ki |
PMID: 8576921 |
NPC20791 | PTGS2 | 1 | 28600 | IC50 |
PMID: 17378609 |
NPC20791 | BLM | 3 |
Median: 28183.8 Range: 28183.8 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | TDP1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | ALDH1A1 | 6 |
Median: 37646 Range: 25118.9 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | CDK6 | 2 |
Median: 25000 Range: 25000 to 25000 |
IC50 |
PMID: 15689157 DOI: 10.1007/s00044-009-9233-5 |
NPC20791 | PTPN1 | 2 |
Median: 23300 Range: 23300 to 23300 |
IC50 |
PMID: 12419367 PMID: 19297174 |
NPC20791 | KMT2A | 1 | 22387.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | AMY1A;AMY1B;AMY1C | 1 | 21400 | IC50 |
PMID: 18507367 |
NPC20791 | SYK | 1 | 20000 | IC50 |
PMID: 22257213 |
NPC20791 | HPGD | 2 |
Median: 21169.9 Range: 19952.6 to 22387.2 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | APEX1 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | CYP2D6 | 1 | 18800 | IC50 |
PMID: 22328583 |
NPC20791 | USP2 | 2 |
Median: 25057.75 Range: 18492.7 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | GPR35 | 1 | 15400 | IC50 |
PMID: 24900447 |
NPC20791 | APP | 1 | 15300 | IC50 |
PMID: 26719209 |
NPC208793 | LMNA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC208793 | CYP1A2 | 1 | 31622.78 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC208793 | CYP2C19 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC209970 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC209970 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC209970 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC209970 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC214067 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC214067 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC216630 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC217226 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC219143 | CYP1A2 | 1 | 39810.72 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC219143 | KDM4E | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC225710 | SELL | 1 | 27600 | IC50 |
PMID: 17302397 |
NPC225710 | GAPDH | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC225710 | MAPK1 | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC225710 | SELP | 1 | 19100 | IC50 |
PMID: 17302397 |
NPC225710 | SMN1;SMN2 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
NPC23155 | MAPT | 2 |
Median: 28370.85 Range: 25118.9 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC23508 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC23508 | HSD17B10 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC243728 | POLB | 1 | 26500 | IC50 |
PMID: 15165161 |
NPC257124 | AR | 2 |
Median: 19027.305 Range: 19000 to 19054.61 |
IC50 |
PMID: 20226658 PMID: 20226658 |
NPC264145 | L3MBTL1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC264145 | POLB | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC264145 | LMNA | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC264145 | KDM4E | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC264145 | XDH | 1 | 15520 | IC50 |
PMID: 12444671 |
NPC281131 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC281131 | GLA | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC281131 | MAPT | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC281131 | LMNA | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC281131 | EPHX2 | 1 | 21760 | IC50 |
PMID: 24679441 |
NPC282895 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC282895 | ALDH1A1 | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC287895 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC287895 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC292792 | PPARA | 1 | 46500 | EC50 |
PMID: 22381047 |
NPC292792 | PPARG | 1 | 40000 | EC50 |
PMID: 22381047 |
NPC292792 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC294902 | HPGD | 3 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC294902 | ALDH1A1 | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC294902 | APEX1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC294902 | APP | 1 | 32800 | IC50 |
PMID: 22921742 |
NPC294902 | AKR1B1 | 1 | 32000 | IC50 |
PMID: 22236472 |
NPC294902 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC294902 | POLB | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC298268 | ALDH1A1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC301585 | PPARD | 1 | 24000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC301585 | PPARG | 1 | 21000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
NPC434 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC434 | HSD17B10 | 2 |
Median: 35716.75 Range: 31622.8 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC434 | CYP3A4 | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC51414 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC51700 | PPARA | 1 | 41310 | EC50 |
PMID: 21855333 |
NPC51700 | AKR1B1 | 1 | 41000 | IC50 |
PMID: 21561086 |
NPC51700 | CYP19A1 | 1 | 32000 | IC50 |
PMID: 18192087 |
NPC51700 | PTPN6 | 1 | 25780 | IC50 |
PMID: 18707891 |
NPC51700 | POLB | 1 | 18600 | IC50 |
PMID: 15165161 |
NPC51700 | CTSD | 1 | 18200 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
NPC51700 | SLCO1B1 | 1 | 15848.93 | IC50 |
PMID: 23571415 |
NPC55412 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC55412 | ALDH1A1 | 2 |
Median: 26651.35 Range: 25118.9 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC55412 | MAPT | 2 |
Median: 23753.05 Range: 22387.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC55412 | CYP3A4 | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC71074 | PTPN6 | 1 | 24560 | IC50 |
PMID: 18707891 |
NPC71074 | PYGM | 1 | 20000 | IC50 |
PMID: 16169219 |
NPC81010 | ESR1 | 1 | 16120 | EC50 |
PMID: 23608764 |
NPC84319 | PYGM | 1 | 28000 | IC50 |
PMID: 16169219 |
NPC84319 | PTPN2 | 1 | 19470 | IC50 |
PMID: 19846303 |
NPC85813 | CYP19A1 | 1 | 48000 | IC50 |
PMID: 16643058 |
NPC85813 | F3 | 1 | 41000 | IC50 |
PMID: 9834151 |
NPC85813 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC85813 | TSHR | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC85813 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC85813 | ALDH1A1 | 1 | 17782.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC96835 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC96835 | ALDH1A1 | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC99886 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC99886 | KDM4E | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC10251 | TSHR | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
NPC1075 | KDM4E | 1 | 11220.2 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC142415 | PTPRF | 2 |
Median: 17055 Range: 11800 to 22310 |
IC50 |
PMID: 21453996 PMID: 27123900 |
NPC142415 | PTPN11 | 1 | 11620 | IC50 |
PMID: 27123900 |
NPC145038 | GAA | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC179950 | ALPL | 1 | 14000 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
NPC179950 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC201844 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | LMNA | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC20791 | PIK3CG | 1 | 13790 | IC50 |
PMID: 25050878 |
NPC20791 | PREP | 1 | 13000 | IC50 |
PMID: 18650094 |
NPC20791 | LCK | 2 |
Median: 13000 Range: 13000 to 13000 |
IC50 |
PMID: 1995903 PMID: 16441060 |
NPC20791 | CALM1;CALM2;CALM3 | 1 | 12970 | IC50 |
PMID: 21129983 |
NPC20791 | PLAU | 1 | 12100 | IC50 |
PMID: 24610996 |
NPC20791 | CA5B | 1 | 11900 | Ki |
PMID: 20185318 |
NPC20791 | CYP2C19 | 1 | 10500 | IC50 |
PMID: 22328583 |
NPC20791 | MMP12 | 1 | 10230 | IC50 |
PMID: 22658537 |
NPC20791 | HIF1AN | 1 | 10200 | IC50 |
PMID: 19822432 |
NPC20791 | CYP2C9 | 1 | 10200 | IC50 |
PMID: 22328583 |
NPC225710 | FUT4 | 1 | 14000 | IC50 |
DOI: 10.1039/C4MD00086B |
NPC23155 | MAPK1 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC257124 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC257124 | PTGS1 | 1 | 11000 | IC50 |
PMID: 16038536 |
NPC264145 | GAA | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC294902 | THRB | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC294902 | CA4 | 1 | 10100 | Ki |
PMID: 20185318 |
NPC434 | HPGD | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC51700 | SLCO1B3 | 1 | 11481.54 | IC50 |
PMID: 23571415 |
NPC55412 | ALOX15 | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC71074 | POLB | 1 | 12600 | IC50 |
PMID: 15165161 |
NPC71074 | HTT | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
NPC71074 | PTPN2 | 1 | 11310 | IC50 |
PMID: 18707891 |
NPC81010 | HCAR2 | 1 | 14000 | Ki |
PMID: 21167710 |
NPC85813 | FABP4 | 2 |
Median: 15650 Range: 13600 to 17700 |
IC50 |
PMID: 20471252 PMID: 25461324 |
NPC85813 | PTGS1 | 1 | 13000 | IC50 |
PMID: 16038536 |