Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC103342 KDM4E 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103342 CYP3A4 1 36200 IC50 PMID: 15270556
NPC104677 CYP2D6 1 43300 IC50 PMID: 22530813
NPC104677 CYP3A4 1 14400 IC50 PMID: 18077363
NPC144995 CYP3A4 1 42600 IC50 PMID: 15270556
NPC164778 HTR1A 1 18020 Ki PMID: 20363635
NPC216921 CYP3A4 1 21800 IC50 PMID: 15270556
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC259957 CYP3A4 1 31600 IC50 PMID: 15646539
NPC293641 CYP3A4 1 36400 IC50 PMID: 15270556
NPC294304 CYP3A4 1 48400 IC50 PMID: 15270556
NPC59951 CYP2D6 1 45500 IC50 PMID: 15270556
NPC59951 CYP3A4 1 21800 IC50 PMID: 15270556
NPC71755 CYP3A4 1 35500 IC50 PMID: 15270556
NPC85707 CYP3A4 1 20600 IC50 PMID: 15646539
NPC91495 L3MBTL1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC91495 CASP1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC91495 TP53 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC91495 CYP19A1 1 28200 IC50 PMID: 16643058
NPC91495 BLM 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC91495 KDM4E 2 Median: 26651.35
Range: 25118.9 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC91495 TDP1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC91495 LMNA 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC91495 HPGD 2 Median: 17900.75
Range: 15848.9 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC103342 RECQL 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862